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Itraconazole Impurity 34

Itraconazole Impurity 34 Basic information
Product Name:Itraconazole Impurity 34
Synonyms:Itraconazole Impurity 34;1,3-Dioxolane-4-methanol, 2-(2,4-dichlorophenyl)-2-(4H-1,2,4-triazol-4-ylmethyl)-, methanesulfonate (ester), (2R,4R)-rel- (9CI);Itraconazole Impurity 44;ItracozoleImpurity16
CAS:103661-14-9
MF:C14H15Cl2N3O5S
MW:408.26
EINECS:
Product Categories:
Mol File:103661-14-9.mol
Itraconazole Impurity 34 Structure
Itraconazole Impurity 34 Chemical Properties
Boiling point 615.5±65.0 °C(Predicted)
density 1.59±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka3.01±0.10(Predicted)
color Pale Brown to Light Brown
Safety Information
MSDS Information
Itraconazole Impurity 34 Usage And Synthesis
Usescis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-4-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate (Itraconazole Impurity 16) is an impurity in the synthesis of Itraconazole (I937500), an orally active antimycotic structurally related to Ketoconazole. Antifungal.
Itraconazole Impurity 34 Preparation Products And Raw materials
trans-Itraconazole N-Desalkyl Itraconazole Butyl Itraconazole KETO ITRACONAZOLE 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine Itraconazole cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl benzoate Des-(1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one) Itraconazole 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE Propyl Itraconazole HYDROXY ITRACONAZOLE 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one (1,2,4-Triazol-4-yl) Itraconazole cis-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl methanesulphonate Itraconazole Impurity 15 cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol
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