ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate

ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate

ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate Basic information
Product Name:ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate
Synonyms:ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate;ethyl 2-(4-hydroxy-3-((hydroxyimino)methyl)phenyl)-4-methylthiazole-5-carboxylate;Febuxostat Impurity 49/ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate;Febuxostat-48;5-Thiazolecarboxylic acid, 2-[3-cyano-4-(1-methylethoxy)phenyl]-4-methyl-, ethyl ester;Febuxostat Isopropyl Isomer Ethyl Ester
CAS:144060-84-4
MF:C17H18N2O3S
MW:330.4
EINECS:
Product Categories:
Mol File:144060-84-4.mol
ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate Structure
ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate Chemical Properties
Melting point 131°C
storage temp. -20°C, Inert atmosphere
solubility Acetonitrile (Slightly), Chloroform (Slightly)
form Solid
color Off-White to Pale Yellow
Safety Information
MSDS Information
ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate Usage And Synthesis
UsesFebuxostat Isopropyl Isomer Ethyl Ester is an intermediate for the synthesis of Febuxostat Isopropyl Isomer (F229045), which is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor.
ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate Preparation Products And Raw materials
isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate FeBuxostat Impurity 26 Febuxostat Descyano Impurity FeBuxostat Impurity 33 Febuxostat impurity 37 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid FeBuxostat Impurity 18 ethyl 2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5- carboxylate 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat Impurity 14 Febuxostat Bromo Impurity 2-(4-(sec-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid FeBuxostat Impurity 32 ethyl 2-(4-butoxy-3-formylphenyl)-4-methylthiazole-5- carboxylate 2-(4-HYDROXY-PHENYL)-4-METHYL-THIAZOLE-5-CARBOXYLIC ACID 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat impurity 36
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