ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyrimidines Methylpyrimidine 2-Amino-4-chloro-6-methylpyrimidine

2-Amino-4-chloro-6-methylpyrimidine

2-Amino-4-chloro-6-methylpyrimidine Basic information
Product Name:2-Amino-4-chloro-6-methylpyrimidine
Synonyms:TIMTEC-BB SBB004134;2-amino-4-chloro-6-methyl-pyrimidin;2-Pyrimidinamine, 4-chloro-6-methyl-;2-AMINO-4-CHLORO-6-METHYLPYRIMIDINE (ACLP);2-Amino-4-chloro-6-methylpyrimidine ,97%;4-Chloro-6-methyl-pyrimidine-2-amine;2-Amino-4-chloro-6-methylpyrimidine,98%;AMR human cell line
CAS:5600-21-5
MF:C5H6ClN3
MW:143.57
EINECS:227-018-3
Product Categories:PYRIMIDINE;Heterocycle-Pyrimidine series;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;FINE Chemical & INTERMEDIATES;Fluorobenzene;Amines;Pyrazines, Pyrimidines & Pyridazines;Pyrimidines;PyrimidinesHeterocyclic Building Blocks;Building Blocks;C4 to C5;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks
Mol File:5600-21-5.mol
2-Amino-4-chloro-6-methylpyrimidine Structure
2-Amino-4-chloro-6-methylpyrimidine Chemical Properties
Melting point 183-186 °C (lit.)
Boiling point 234.32°C (rough estimate)
density 1.2986 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility acetic acid: soluble50mg/mL, clear, colorless to faintly yellow
pka4.26±0.10(Predicted)
form Solid
color White to Off-White
Water Solubility Insoluble in water.
BRN 114297
CAS DataBase Reference5600-21-5(CAS DataBase Reference)
NIST Chemistry Reference2-Amino-4-chloro-6-methylpyrimidine(5600-21-5)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-20/21/22
Safety Statements 22-24/25-37/39-26-36
WGK Germany 3
RTECS UV6329600
HazardClass IRRITANT, AVOID SKIN CONTACT
HS Code 29335995
MSDS Information
ProviderLanguage
2-Amino-4-chloro-6-methylpyrimidine English
SigmaAldrich English
ACROS English
ALFA English
2-Amino-4-chloro-6-methylpyrimidine Usage And Synthesis
Chemical PropertiesWHITE TO LIGHT YELLOW NEEDLE-LIKE CRYST. POWDER
Uses2-Amino-4-chloro-6-methylpyrimidine was used to study the influence of chlorine substitution in pyrimidine ring on proton donor ability of amino group in 2-aminopyrimidine.
DefinitionChEBI: An aminopyrimidine compound having its amino group at position 2 and chloro and methyl substituents at positions 4 and 6 respectively.
General Description2-Amino-4-chloro-6-methylpyrimidine is a nitification inhibitor.
Purification MethodsRecrystallise it from EtOH. [Beilstein 24 H 84.]
2-(((6-CHLORO-4-METHYLPYRIMIDIN-2-YL)AMINO)METHYLENE)-5-PHENYLCYCLOHEXANE-1,3-DIONE 4-chloro-N-ethyl-6-(trifluoromethyl)-2-pyrimidinamine 3-[(4-CHLORO-6-METHYLPYRIMIDIN-2-YL)AMINO]-2-(3-[(PHENYLTHIO)METHYL]BENZOYL)ACRYLONITRILE 2-Amino-4-chloro-6-methylpyrimidine (((6-CHLORO-4-METHYLPYRIMIDIN-2-YL)AMINO)METHYLENE)METHANE-1,1-DICARBONITRILE 3-[(4-CHLORO-6-METHYLPYRIMIDIN-2-YL)AMINO]-2-(PROPYLSULFONYL)ACRYLONITRILE 2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE 4-(4-CHLORO-6-METHYL-2-PYRIMIDINYL)MORPHOLINE 4-CHLORO-5-ETHYL-6-METHYL-PYRIMIDIN-2-YLAMINE 3-[(4-CHLORO-6-METHYLPYRIMIDIN-2-YL)AMINO]-2-(3-METHOXYBENZOYL)ACRYLONITRILE 2-(4-CHLOROBENZOYL)-3-[(4-CHLORO-6-METHYLPYRIMIDIN-2-YL)AMINO]ACRYLONITRILE 3-[(4-CHLORO-6-METHYLPYRIMIDIN-2-YL)AMINO]-2-[(4-CHLOROPHENYL)SULFONYL]ACRYLONITRILE 2-(2-CHLOROBENZOYL)-3-[(4-CHLORO-6-METHYLPYRIMIDIN-2-YL)AMINO]ACRYLONITRILE 2-Anilino-4-chloro-6-methylpyrimidine 3-([(4-CHLORO-6-METHYLPYRIMIDIN-2-YL)AMINO]METHYLIDENE)-1,5,6-TRIMETHYL-1,2,3,4-TETRAHYDRO-2LAMBDA6-THIENO[2,3-C][1,2]THIAZINE-2,2,4-TRIONE Pirimiphos-methyl Tris(hydroxymethyl)aminomethane N,N-Dimethyl-1,4-phenylenediamine
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