2,5-Dichlorophenylboronic acid

2,5-Dichlorophenylboronic acid Basic information
Product Name:2,5-Dichlorophenylboronic acid
Synonyms:2,5-Dichlorophenylboronic acid ,98%;2,5-Dichlorophenylboronic acid,97%;2,5-Dichlorophenylbo;AKOS BRN-0160;2,5-DICHLOROBENZENEBORONIC ACID;2,5-DICHLOROPHENYLBORONIC ACID;RARECHEM AH PB 0097;2,5-Dichlorophenylboronic
CAS:135145-90-3
MF:C6H5BCl2O2
MW:190.82
EINECS:
Product Categories:Aryl Boronic Acids;Boronic Acids and Derivatives;Chemical Synthesis;Disubstituted Aryl Boronic Acids;Organometallic Reagents;Boronate Ester;Aryl;Organoborons;Boronic Acids;Boronic Acids and Derivatives;Boronic acids;Heterocyclic Compounds;Boronic Acid;blocks;BoronicAcids;Boronic Acid series;Potassium Trifluoroborate;B (Classes of Boron Compounds)
Mol File:135145-90-3.mol
2,5-Dichlorophenylboronic acid Structure
2,5-Dichlorophenylboronic acid Chemical Properties
Melting point 150 °C(lit.)
Boiling point 343.6±52.0 °C(Predicted)
density 1.47±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Acetone (Slightly), Methanol (Slightly)
pka7.26±0.58(Predicted)
form Powder
color White to off-white
BRN 4801290
InChIKeyNNTFPBXQPOQRBT-UHFFFAOYSA-N
CAS DataBase Reference135145-90-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37/39-36
WGK Germany 3
HazardClass IRRITANT
HS Code 29163990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
2,5-Dichlorophenylboronic acid Usage And Synthesis
Chemical PropertiesWhite to off-white powder
Usessuzuki reaction
UsesReactant for:• ;Regioselective iodination using silver salts1• ;Pd-catalyzed Suzuki-Miyaura coupling2• ;Rhodium(I)-catalyzed carbonylative cyclization of alkynes3• ;Copper catalyzed coupling reactions4
Uses2,5-Dichlorophenylboronic Acid is a reactant in the synthesis of Dipeptidyl peptidase IV (DPP4) inhibitors for the treatment of type 2 diabetes.
2,5-Dichlorophenylboronic acid Preparation Products And Raw materials
Raw materialsTetrahydrofuran-->n-Butyllithium-->Trimethyl borate-->2-Bromo-1,4-dichlorobenzene
4-Chlorophenylboronic acid 3,5-Dichlorophenylboronic acid 4-(BENZYLOXY)-3,5-DICHLOROPHENYLBORONIC ACID Ascoric Acid Lobenzarit disodium Phenylboronic acid 4-ETHOXY-3,5-DICHLOROPHENYLBORONIC ACID 3,4-DICHLOROPHENYLBORONIC ACID, PINACOL ESTER 3,5-Dimethylphenylboronic acid p-Dichlorobenzene (2,5-DICHLORO-3-FORMYLPHENYL)BORONIC ACID 3-(Benzyloxy)-2,4-dichlorophenylboronic acid 3,5-DICHLOROPHENYLBORONIC ACID, PINACOL ESTER Permethrin Boric acid 2,4-DICHLOROPHENYLBORONIC ACID, PINACOL ESTER 2,4-Dichlorobenzyl chloride 2,4,5-Trichlorophenylboronic acid

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