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| | Azulene Basic information |
| | Azulene Chemical Properties |
| Melting point | 98-100 °C(lit.) | | Boiling point | 242 °C(lit.) | | density | 1.0530 | | refractive index | 1.5736 (estimate) | | Fp | 241-243°C | | storage temp. | Store at +2°C to +8°C. | | solubility | Soluble in organic solvents. | | form | Fine Crystalline Powder | | color | Dark blue | | Merck | 14,926 | | BRN | 969517 | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. | | InChIKey | CUFNKYGDVFVPHO-UHFFFAOYSA-N | | LogP | 3.200 | | CAS DataBase Reference | 275-51-4(CAS DataBase Reference) | | EPA Substance Registry System | Azulene (275-51-4) |
| Hazard Codes | N | | Risk Statements | 51/53 | | Safety Statements | 61 | | RIDADR | UN 3077 9/PG 3 | | WGK Germany | 2 | | RTECS | CO4570000 | | F | 8 | | TSCA | Yes | | HS Code | 29029000 | | Toxicity | LD50 orl-rat: >4 g/kg DRUGAY 6,13,82 |
| | Azulene Usage And Synthesis |
| Chemical Properties | Azulene is a blue crystalline compound with the chemical formula C10H8 and a melting point of 99°C. It contains afive-membered ring fused to a seven-membered ring and has aromatic properties. When heated it is converted into naphthalene. | | Uses | azulene is renowned as an anti-inflammatory, calming, and soothing agent. excellent for sensitive skin, azulene is a german chamomile derivative with a characteristic deep blue color. Careful, it stains! | | Uses | Azulene is used as an additive in ointments. It is an active ingredient in cosmetics, shaving creams and other topicals. It is used as antioxidant and in anti-inflammatory activities. It is involved in the colorimetric determination of furfural. It acts as ligand for low valent metals and forms pi complexes with both cyclopentadienyl and cylcloheptatrienyl ligands in organometallic chemistry. It is also used as precursor for the preparation of (azulene)Mo2 (CO)6 and (azulene)Fe2 (CO)5. | | Definition | ChEBI: Azulene is a mancude carbobicyclic parent consisting of a cycloheptatriene and cyclopentadiene rings. It has a role as a plant metabolite and a volatile oil component. It is an ortho-fused bicyclic arene, a member of azulenes and a mancude carbobicyclic parent. | | Synthesis Reference(s) | Journal of the American Chemical Society, 75, p. 2386, 1953 DOI: 10.1021/ja01106a030
Tetrahedron Letters, 23, p. 495, 1982 DOI: 10.1016/S0040-4039(00)86871-9 | | Safety Profile | Poison by intraperitoneal,intravenous, and subcutaneous routes. When heated todecomposition it emits acrid smoke and irritating vapors. | | Source | Azulene is a natural product and function as pigment in living organisms like plants, fungi etc. This compound was first isolated from the German Chamomile and later from yarrow, wormwood and other plants as oily liquid. | | Purification Methods | Crystallise azulene from EtOH. It has UV max 270nm (log 4.72) in hexane. [Platner & Magyar Helv Chim Acta 25 581 1942, Beilstein 5 IV 1636.] |
| | Azulene Preparation Products And Raw materials |
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