(R)-(+)-1,2,4-BUTANETRIOL

(R)-(+)-1,2,4-BUTANETRIOL Basic information
Product Name:(R)-(+)-1,2,4-BUTANETRIOL
Synonyms:1,2,4-BUTANETRIOL, (R);(R)-(+)-1,2,4-BUTANETRIOL;(R)-1,2,4-BUTANETRIOL;(R)-(+)-1,2,4-TRIHYDROXYBUTANE;(R)-(+)-1,2,4-TRIYDROXYBUTANE;(R)-(+)-1 2 4-BUTANETRIOL 98% &;(R)-Butane-1,2,4-triol;(2R)-(+)-1,2,4-Trihydroxybutane
CAS:70005-88-8
MF:C4H10O3
MW:106.12
EINECS:
Product Categories:Chiral Building Blocks;Organic Building Blocks;Polyols
Mol File:70005-88-8.mol
(R)-(+)-1,2,4-BUTANETRIOL Structure
(R)-(+)-1,2,4-BUTANETRIOL Chemical Properties
Boiling point 150
alpha +26°(20/D, c=1, CH3OH)
density 1.19 g/mL at 25 °C(lit.)
refractive index n20/D 1.474
Fp 110 °C
storage temp. Sealed in dry,Room Temperature
solubility Methanol (Sparingly), Water (Slightly)
pka14.02±0.20(Predicted)
form Oil
color Yellow to Dark Yellow
Specific Gravity1.190
optical activity[α]20/D +28±2, c = 1 in methanol
BRN 4652491
Stability:Hygroscopic
InChIKeyARXKVVRQIIOZGF-SCSAIBSYSA-N
CAS DataBase Reference70005-88-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
3-10-21
MSDS Information
ProviderLanguage
SigmaAldrich English
(R)-(+)-1,2,4-BUTANETRIOL Usage And Synthesis
Chemical Propertiescolorless liquid
Uses(R)?-?(+?)?-?1,?2,?4-?Butanetriol is a reagent used in organic synthesis including the preparation of the steroid hormone 1α,?25-?dihydroxyvitamin D3 which is the most active metabolite of vitamin D3 exerting control over a plethora of biological processes.
Uses(R)-(+)-1,2,4-Butanetriol can be used as a reactant to prepare:
  • Phenanthrene 9, 10 diacetal from phenanthrene 9, 10 quinone.
  • (R)-1,2,4-Tris(benzoyloxy)butane by reacting with benzyl chloride in the presence of a base and DMAP.

(R)-(+)-1,2,4-BUTANETRIOL Preparation Products And Raw materials
Preparation Products(R)-4-Benzyloxy-1,3-butanediol
D-RIBULOSE (-)-1,4-DI-O-TOSYL-2,3-O-ISOPROPYLIDENETHREITOL Gluconic acid Chlorogenic acid 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol MUCIC ACID HEXA(2-CYANOETHOXY) CYCLOHEXANE EPI-INOSITOL 2-Naphthyl-beta-D-galactopyranoside SODIUM DIHYDROXYTARTRATE Quinic acid D-GLUCOSE DIETHYL MERCAPTAL G-STROPHANTHIN adipiodone, dimeglumine salt Sorbitol 2-KETO-D-GLUCONIC ACID HEMICALCIUM SALT D(+)-Malic acid 2,5-O-METHYLENE-D-MANNITOL

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