ChemicalBook Product Catalog Biochemical Engineering Amino Acids and proteins L-Isovaline

L-Isovaline

L-Isovaline Basic information
Product Name:L-Isovaline
Synonyms:L(+)-Isovaline Monohydrate;2,3-Dimethylalanine;2-azanyl-2-methyl-butanoic acid;L(+)-Isovaline Monohydrate, (>99% ee), 99+% 250MG;(S)-Α-ETHYLALANINE·H2O;α-Me-Gly(Ethyl)-OH·H2O;(S)-(+)-2-Amino-2-methylbutanoicacidmonohydrate(e.e.);(S)-(+)-2-AMINO-2-METHYLBUTANOIC ACID 1-HYDRATE (E.E.)
CAS:595-40-4
MF:C5H11NO2
MW:117.15
EINECS:
Product Categories:Amino Acid Derivatives;Valine [Val, V];unnatural amino acids;pharmacetical;α-Methyl Amino Acids
Mol File:595-40-4.mol
L-Isovaline Structure
L-Isovaline Chemical Properties
Melting point 289.39°C (estimate)
Boiling point 213.6±23.0 °C(Predicted)
alpha D25 +11.13° (c = 5 in H2O)
density 1.2000 (estimate)
refractive index 1.4650 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka2.38±0.10(Predicted)
form Fine Crystalline Powder
color White
CAS DataBase Reference595-40-4(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
TSCA No
MSDS Information
ProviderLanguage
ACROS English
L-Isovaline Usage And Synthesis
Usesa-Me-Gly(Ethyl)-OH is used in preparation of peptide compound comprising highly sterically hindered amino acid via reaction of electron-withdrawing group-protected N-unsubstituted-α,α-disubstituted amino acid with peptide followed by N-alkylation.
Purification MethodsCrystallise it from aqueous Me2CO, or better by dissolving in H2O and adding excess Me2CO. [Baker et al. J Am Chem Soc 74 4701 1952, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 2573-2577 1961.]
L-Isovaline Preparation Products And Raw materials
PYROGLU-HIS-GLY-CYCLOLEU L-Isovaline ALPHA-METHYL-L-P-TYROSINE ALTRENOGEST Valine Dimethyl methyldopa (1S,3R)-ACPD 2,2-Bis(hydroxymethyl)butyric acid MCPB alpha-Methyldopa sesquihydrate DIETHYL 2-(ACETYLAMINO)-2-[4-(METHOXYCARBONYL)BENZYL]MALONATE (+/-)-1-AMINOCYCLOPENTANE-CIS-1,3-DICARBOXYLIC ACID DIETHYL 2-(ACETYLAMINO)-2-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHYL)MALONATE AMINO ACIDS 1-AMINOCYCLOBUTANE-CIS-1,3-DICARBOXYLIC ACID α-Hydroxymethyl-L-tyrosine DIMETHYL 5-(2-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)ETHYL)-4,6-DIOXOTETRAHYDRO-2H-PYRROLO[3,4-D]ISOXAZOLE-3,3(3AH)-DICARBOXYLATE (S)-(+)-2-AMINO-2-METHYLBUTANEDIOIC ACID
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