ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Glycine derivative 4-Phosphonophenylglycine

4-Phosphonophenylglycine

4-Phosphonophenylglycine Basic information
Product Name:4-Phosphonophenylglycine
Synonyms:(RS)-PHOSPHONOPHENYLGLYCINE;(RS)-PPG;(RS)-4-PHOSPHONOPHENYLGLYCINE;4-Phosphonophenylglycine;Benzeneacetic acid, α-amino-4-phosphono-;2-(4-phosphonoanilino)aceticaci;4-Phosphonophenylglycine USP/EP/BP;(RS)PPG,(RS) PPG
CAS:120667-15-4
MF:C8H10NO5P
MW:231.14
EINECS:
Product Categories:Glutamate receptor
Mol File:120667-15-4.mol
4-Phosphonophenylglycine Structure
4-Phosphonophenylglycine Chemical Properties
Boiling point 515.5±60.0 °C(Predicted)
density 1.61±0.1 g/cm3(Predicted)
storage temp. Store at RT
solubility DMSO: soluble2mg/mL
form solid
pka1.60±0.10(Predicted)
Safety Information
WGK Germany 3
MSDS Information
4-Phosphonophenylglycine Usage And Synthesis
Uses(RS)-PPG is a potent and selective group III mGluR agonist.
Biological ActivityA potent and selective group III metabotropic glutamate receptor agonist, with approximately 25-fold preference for hmGlu 8 ; anticonvulsant and neuroprotective in vivo . Also available as part of the Group III mGlu Receptor Tocriset™ .
4-Phosphonophenylglycine Preparation Products And Raw materials
IBOTENIC ACID L-AP4 AIDA (S)-APIC (RS)-1-AMINO-5-PHOSPHONOINDAN-1-CARBOXYLIC ACID 4-Phosphonophenylglycine Triethyl phosphonoacetate MPPG Benfotiamine RS-ALPHA-CYCLOPROPYL-[3-3H]-4-PHOSPHONOPHENYLGLYCINE 4-Aminophenylacetic acid CPPG ALPHA-METHYL-3-METHYL-4-PHOSPHONOPHENYLGLYCINE Phthalic anhydride (S)-MPPG 4-Hydroxy-D-(-)-2-phenylglycine D-2-Phenylglycine
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