3-AMINO-ISONICOTINIC ACID METHYL ESTER

3-AMINO-ISONICOTINIC ACID METHYL ESTER Basic information

Product Name:	3-AMINO-ISONICOTINIC ACID METHYL ESTER
Synonyms:	METHYL 3-AMINOPYRIDINE-4-CARBOXYLATE;METHYL 3-AMINOISONICOTINATE;AKOS 93360;3-AMINO-ISONICOTINIC ACID METHYL ESTER;3-AMINO-4-PYRIDINECARBOXYLIC ACID METHYL ESTER;3-AMINOPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER;3-Amino-isonicotinic acid methyl ester ,98%;Tpc-py003
CAS:	55279-30-6
MF:	C7H8N2O2
MW:	152.15
EINECS:	689-872-7
Product Categories:	Pyridine;pharmacetical;Esters;Pyridines
Mol File:	55279-30-6.mol

3-AMINO-ISONICOTINIC ACID METHYL ESTER Chemical Properties

Melting point	84-86
Boiling point	292.5±20.0 °C(Predicted)
density	1.238±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to crystal
pka	4.05±0.18(Predicted)
color	White to Yellow to Green
CAS DataBase Reference	55279-30-6(CAS DataBase Reference)

Safety Information

MSDS Information

3-AMINO-ISONICOTINIC ACID METHYL ESTER Usage And Synthesis

Chemical Properties	Yellow powder
Uses	3-Aminoisonicotinic Acid Methyl Ester is a useful synthetic intermediate. It is used in the synthesis of morpholinophenylquinazolines and related derivatives as PI3 kinase p110α inhibitors. It is also used to synthesize aryl tetrahydropyridine inhibitors of farnesyltransferase as antitumor agents.

3-AMINO-ISONICOTINIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials	Sodium hydroxide-->Ethyl acetate-->Methanol-->Dichloromethane-->Acetic acid-->Thionyl chloride-->Government regulation-->Acetic anhydride-->Sodium bicarbonate-->Acetamide-->3,4-Pyridinedicarboxylic acid
Preparation Products	3-AMINO-4-PYRIDINECARBOXAMIDE-->METHYL 3-HYDROXYISONICOTINATE

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