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| | Tri-tert-butylphosphine tetrafluoroborate Basic information | | Reaction |
| | Tri-tert-butylphosphine tetrafluoroborate Chemical Properties |
| Melting point | 261 °C(lit.) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly) | | form | Crystals and Chunks | | color | White | | Water Solubility | Soluble in methylene chloride and chloroform. Slightly soluble in terahydro furan. Insoluble in hexane, toluene and water. | | Sensitive | Hygroscopic | | BRN | 8813613 | | InChIKey | YSTLBJVHZMEEAC-UHFFFAOYSA-N | | CAS DataBase Reference | 131274-22-1(CAS DataBase Reference) |
| | Tri-tert-butylphosphine tetrafluoroborate Usage And Synthesis |
| Reaction |
- Air-stable, non-pyrophoric precursor of the Tri-t-butylphosphine ligand which is used in a variety of catalytic processes.
- Ligand for Suzuki cross-couplings.
- Ligand for Heck Reactions.
- Ligand for Stille Cross-couplings.
- Ligand for α-Arylation and vinylation of arylmandelic acid derivatives.
- Ligand for direct arylation of hetercycles
- Synthesis of benzocyclobutenes by C-H activation.
- Cross-coupling of Grignard reagents and aryl bromides.
- Palladium catalyzed annulation of haloanilines.
- Palladium-Catalyzed Acylation.
- Palladium Catalyzed Carbonylative Heck Reaction.
- Palladium-catalyzed aminosulfonylation.
- Palladium-catalyzed intramolecular C–O bond formation.
- Ruthenium-catalyzed cross-coupling of aldehydes with arylboronic acid.
| | Chemical Properties | white to light yellow crystal powde | | Uses | suzuki reaction
Hindered Phosphine salt employed with a Pd(0)-15-membered, triolefinic, macrocyle in Suzuki cross-coupling reactions of aryl bromides and chlorides. Also used in Heck coupling of non-activated vinyl tosylates with electron deficient olefins.
Ligand used in the Pd-catalyzed enantioselective α?arylation of N-boc-pyrrolidine. | | Uses | Tri-tert-butylphosphonium Tetrafluoroborate is used in the synthesis of substituted biaryl compounds via palladium catalyzed tandem Heck-direct arylation and tandem- sequential Heck-direct arylation-hydrogenation. Also used in the synthesis of a novel organic dye with fluorenone as conjugation bridge which is used in dye sensitized solar cells. | | Application | Tri-tert-butylphosphonium tetrafluoroborate is a ligand used in the palladium-catalyzed enantioselective alfa-arylation of N-boc-pyrrolidine. It is also used with a palladium(0)-15-membered, triolefinic, macrocyle in Suzuki cross-coupling reactions of aryl bromides and chlorides. Further, it is used in the Heck coupling of vinyl tosylates with olefins. |
| | Tri-tert-butylphosphine tetrafluoroborate Preparation Products And Raw materials |
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