ChemicalBook Product Catalog Organic Chemistry Carboxylic acids and derivatives Carboxylic acid esters and derivatives Ethyl 2-fluoropropionate

Ethyl 2-fluoropropionate

Ethyl 2-fluoropropionate Basic information
Product Name:Ethyl 2-fluoropropionate
Synonyms:2-fluoro-ethyl propionate;ethyl 2-fluoropropanoate;2-fluoropropanoic acid ethyl ester;2-FLUOROPROPIONIC ACID ETHYL ESTER;Ethyl 2-fluoropropionate;(127306-59-6) ethyl 2-fluoropropionate;Ethyl2-Fluoropropionate>;Propanoic acid, 2-fluoro-, ethyl ester
CAS:349-43-9
MF:C5H9FO2
MW:120.12
EINECS:
Product Categories:Fluorinated Building Blocks;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Synthetic Organic Chemistry
Mol File:349-43-9.mol
Ethyl 2-fluoropropionate Structure
Ethyl 2-fluoropropionate Chemical Properties
Boiling point 125°C
density 0.997
refractive index 1.3750-1.3790
Fp 29°C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form clear liquid
color Colorless to Light yellow to Light orange
InChIKeyODMITNOQNBVSQG-UHFFFAOYSA-N
CAS DataBase Reference349-43-9(CAS DataBase Reference)
Safety Information
Hazard Codes F
Risk Statements 10-36/38
Safety Statements 16-36/37/39-3/9/49-26
RIDADR 3272
HazardClass FLAMMABLE
PackingGroup III
HS Code 29155090
MSDS Information
Ethyl 2-fluoropropionate Usage And Synthesis
Chemical PropertiesClear colorless to light yellow liquid
UsesEthyl 2-fluoropropionate is used as a solvent for lithium secondary batteries. Ethyl-2-fluoropropionate is also used as a reagent to synthesize a series of potent Nicotinic Acid (N429250) receptor agonists for the treatment of dyslipidemia, a health condition characterized by high triglyceride levels.
Synthesis Reference(s)The Journal of Organic Chemistry, 55, p. 2311, 1990 DOI: 10.1021/jo00295a016
Ethyl 2-fluoropropionate Preparation Products And Raw materials
Ethyl 4,4,4-trifluoroacetoacetate Fluticasone propionate Ethyl bromodifluoroacetate Ethanol Ethyl 2-fluoropropionate Ethyl pyruvate Ethyl propionate Ethyl formate Tris(trimethylsilyl)phosphate Ethylparaben Ethyl trifluoroacetate ISOXADIFEN-ETHYL Ethyl acetate Ethyl oleate Ethyl levulinate Ethyl acrylate Methyl acrylate Ethyl cyanoacetate
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