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Menthone 1,2-glycerol ketal

Menthone 1,2-glycerol ketal Basic information
Product Name:Menthone 1,2-glycerol ketal
Synonyms:L-MENTHONE-1,2-GLYCERYL KETAL;FEMA 3807;1,4-Dioxaspiro4.5decane-2-methanol, 9-methyl-6-(1-methylethyl)-;9-Methyl-6-(1-methylethyl)-1,4-dioxaspiro-[4,5]decan-2-methanol;6-ISOPROPYL-9-METHYL-1,4-DIOXASPIRO[4.5]DECANE-2-METHANOL;MENTHONE GLYCERIN ACETAL;Menthone 1,2-glycerol ketal;2-hydroxymethyl-9-methyl-6-(1-methylethyl)-1,4-dioxaspiro[4.5]decane
CAS:63187-91-7
MF:C13H24O3
MW:228.33
EINECS:408-200-3
Product Categories:
Mol File:63187-91-7.mol
Menthone 1,2-glycerol ketal Structure
Menthone 1,2-glycerol ketal Chemical Properties
Boiling point 148-152 °C(Press: 14 Torr)
density 1.04±0.1 g/cm3(Predicted)
vapor pressure 0.2Pa at 25℃
FEMA 3808 | D,L-MENTHONE 1,2-GLYCEROL KETAL
solubility Chloroform (Slightly), Methanol (Slightly)
pka14.21±0.10(Predicted)
form Thick Oil
color Colourless
Odorat 100.00 %. odorless
Odor Typeodorless
Water Solubility 1.2g/L at 20℃
JECFA Number445
LogP3.04 at 25℃
EPA Substance Registry System1,4-Dioxaspiro[4.5]decane-2-methanol, 9-methyl-6-(1-methylethyl)- (63187-91-7)
Safety Information
Hazard Codes Xi
Risk Statements 38-41-52/53
Safety Statements 26-37/39-61
MSDS Information
Menthone 1,2-glycerol ketal Usage And Synthesis
Chemical PropertiesMenthone 1,2-glycerol ketal is Colorless viscous liquid
Chemical PropertiesMenthone 1,2-glycerol ketal is a clear, colorless, pale, viscous liquid and creates a physiological cooling sensation on the skin or mucosa. The material is mainly used to create a cooling effect in cosmetic preparations used on the skin.
The material is prepared by acetalization of l-menthone with glycerine.
Chemical Propertiesl-Menthone 1,2-glycerol ketal has a mint, menthol taste.
Usesis therapeutic agent containing TRPM8 agonist for treating gastrointestinal disorders and abdominal pain.
UsesMenthone 1,2-glycerol ketal is used for adding fragrance, and to leave the skin feeling refreshed and cool. It is a menthol derivative that can be naturally obtained or synthetically manufactured.
DefinitionChEBI: Menthone 1,2-glyceryl ketal is a p-menthane monoterpenoid.
Aroma threshold valuesAroma characteristics at 10%: little or no odor.
Taste threshold valuesTaste characteristics at 5 to 100 ppm: a clean crisp coolness on palate starting out low but growing. The coolness is readily apparent in the throat. A slight tingling or burning sensation accompanies the coolness. The flavor character is lingering and apparently cumulative in effect.
Trade nameFrescolate MGA (Symrise)
Menthone 1,2-glycerol ketal Preparation Products And Raw materials
Pentanedioic acid, 1-[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl] ester Menthyl acetate Triethanolamine oleic soap Menthone 1,2-glycerol ketal 1,2-Pentanediol 1-MENTHOL-ETHYLENEGLYCOLCARBONATE Cornmint oil Menthoxypropanediol FEMA 2542 L-Menthone-1,2-Glycerol Ketal Menthone 1,2-glycerol ketal L-MENTHONE Menthone 2-(1-ethylpentyl)-1,3-dioxolane-4-methanol 2-ISOBUTYL-4-METHYL-1,3-DIOXOLANE L-MENTHONE-1,2-GLYCEROL KETAL OR 2-HYDROXYMETHYL-6-ISOPROPYL-9-METHYL-1,4-DIOXASPIROL[4,5]DECANE GLYKETAL MENTHONE
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