ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Methylpyridine 3-Chloro-5-(trifluoromethyl)pyridin-2-amine

3-Chloro-5-(trifluoromethyl)pyridin-2-amine

3-Chloro-5-(trifluoromethyl)pyridin-2-amine Basic information
Product Name:3-Chloro-5-(trifluoromethyl)pyridin-2-amine
Synonyms:TIMTEC-BB SBB003584;LABOTEST-BB LT00012608;2-AMINO-3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE;2,3,5-actf;3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINAMINE;3-Chloro-5-(trifluoromethyl)-2-pyridylamine;3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-2-AMINE;3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE-2-AMINE
CAS:79456-26-1
MF:C6H4ClF3N2
MW:196.56
EINECS:401-670-0
Product Categories:Fluorine series;amine| alkyl chloride;Chloropyridines;C6Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyridines, Pyrimidines, Purines and Pteredines;Pyridine series;Amines;Pyridines;Pyridine;Halopyridines
Mol File:79456-26-1.mol
3-Chloro-5-(trifluoromethyl)pyridin-2-amine Structure
3-Chloro-5-(trifluoromethyl)pyridin-2-amine Chemical Properties
Melting point 86-90 °C (lit.)
Boiling point 205°C
density 1.4650 (estimate)
vapor pressure 40.8Pa at 24.85℃
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Chloroform (Slightly), Methanol (Slightly)
pka1.79±0.49(Predicted)
form Crystalline Powder
color White to off-white
Water Solubility 622mg/L at 25℃
InChIKeyWXNPZQIRDCDLJD-UHFFFAOYSA-N
LogP2.59 at 20℃
CAS DataBase Reference79456-26-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-52/53-36/37/38-20/21/22
Safety Statements 61-36/37/39-26-22
WGK Germany 2
HazardClass IRRITANT
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
3-Chloro-5-(trifluoromethyl)pyridin-2-amine Usage And Synthesis
Chemical PropertiesLight yellow Cryst
Uses2-?Amino-?3-?chloro-?5-?trifluoromethylpyrid?ine acts as a reactant in the synthesis of novel imidazo[1,2-a]pyridine-coumarin hybrid molecules as inhibitors of NS5B in potential treatment of Hepititis C.
DefinitionChEBI: 3-Chloro-5-(trifluoromethyl)pyridin-2-amine is an aminopyridine.
3-Chloro-5-(trifluoromethyl)pyridin-2-amine Preparation Products And Raw materials
Preparation ProductsFluazinam-->IMidazo[1,2-a]pyridine, 8-chloro-6-(trifluoroMethyl)-
Betaine 3-Chloro-5-(trifluoromethyl)pyridin-2-amine 2-Chloro-5-chloromethylpyridine 4-Methylpyridine ALTRENOGEST 2-Amino-3-picoline 2-Chloro-5-trifluoromethylpyridine 3-Aminopyridine Glycine Difluorochloromethane Trifluoromethyl Aniline Bis(2-ethylhexyl)amine 2-Aminopyridine Tris(hydroxymethyl)aminomethane Epichlorohydrin AMINO ACIDS 4-Dimethylaminopyridine
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