|
| | 2,4-Difluorophenol Basic information |
| Product Name: | 2,4-Difluorophenol | | Synonyms: | 2,4-Difluorophenol 98%;4-Difluorophenol;2,4- twodifluoro phenol;2,4-Difluorophenol 98%, 4-Difluorophenol 98%;2,4-DIFLUOROPHENOL;Phenol, 2,4-difluoro-;2,4-Difluorophenol, 98+%;2,4-Difluorophenol, 99+% | | CAS: | 367-27-1 | | MF: | C6H4F2O | | MW: | 130.09 | | EINECS: | 206-688-0 | | Product Categories: | Organic Building Blocks;Oxygen Compounds;Fluoro-Aromatics;Aromatic Phenols;Fluorobenzene;Phenols;Phenol&Thiophenol&Mercaptan;Fluorophenols;Heterocyclic Acids,Quinolines | | Mol File: | 367-27-1.mol |  |
| | 2,4-Difluorophenol Chemical Properties |
| Melting point | 22.4 °C (lit.) | | Boiling point | 52-53 °C/19 mmHg (lit.) | | density | 1.362 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.486(lit.) | | Fp | 134 °F | | storage temp. | Inert atmosphere,Room Temperature | | pka | 8.72±0.18(Predicted) | | form | powder to lump to clear liquid | | color | White or Colorless to Yellow | | Specific Gravity | 1.362 | | Water Solubility | slightly soluble | | BRN | 1934803 | | InChIKey | NVWVWEWVLBKPSM-UHFFFAOYSA-N | | CAS DataBase Reference | 367-27-1(CAS DataBase Reference) | | NIST Chemistry Reference | 2,4-Difluorophenol(367-27-1) |
| | 2,4-Difluorophenol Usage And Synthesis |
| Chemical Properties | clear yellow-green liquid after melting | | Uses | 2,4-Difluorophenol, is an organic building block used for the synthesis of various pharmaceutical compounds, such as antivirulence agents. It is also used in the synthesis of new α-Phenoxyacetamide derivatives, acting as type III secretion system of Pseudomonas aeruginosa PAO1, a gram-negative bacteria. | | Uses | 2,4-Difluorophenol has been used:
- as starting reagent during the synthesis of 4,6-difluoro-5,7-dihydroxytryptamine
- in the synthesis of 3-carboxy-6,8-difluoro-7-hydroxycoumarin (Pacific Blue), fluorinated fluorescent dye
|
| | 2,4-Difluorophenol Preparation Products And Raw materials |
| Raw materials | 2,4-Dichloronitrobenzene-->2,5-Difluorophenol-->1,4-Difluorobenzene | | Preparation Products | 3-(2,4-difluorophenoxy)propanoic acid-->3-AMINO-2-(2,4-DIFLUOROPHENOXY)PYRIDINE-->2,4-DIFLUORO-6-NITROPHENOL-->2,4-Difluoro-5-nitrophenol-->2-Bromo-4,6-difluorophenol-->ABBV-075-->4-Fluorophenol-->AKOS B013914-->3-Ethoxy-2,6-difluorobenzaldehyde-->2-(2,4-difluorophenoxy)aniline-->4'-(2,4-DIFLUOROPHENOXY)ACETOPHENONE-->7,9-difluoro-2,3,4,5-tetrahydro-1-benzoxepin-5-one |
|
