Lesinurad Impurity J

Lesinurad Impurity J Basic information
Product Name:Lesinurad Impurity J
Synonyms:2-((5-bromo-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid;Lesinurad Impurity 9 (Lesinurad Impurity E);Lesinurad Impurity J;Lesinurad Impurity 1/2-[[5-Bromo-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid;Resinad Impurity I: Decyclocycloresinad;Acetic acid, 2-[[5-bromo-4-(1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-
CAS:1210330-64-5
MF:C14H10BrN3O2S
MW:364.22
EINECS:
Product Categories:
Mol File:1210330-64-5.mol
Lesinurad Impurity J Structure
Lesinurad Impurity J Chemical Properties
Boiling point 617.6±57.0 °C(Predicted)
density 1.69±0.1 g/cm3(Predicted)
pka2.91±0.10(Predicted)
Safety Information
MSDS Information
Lesinurad Impurity J Usage And Synthesis
Uses2-[[5-Bromo-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout.
Lesinurad Impurity J Preparation Products And Raw materials
4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione Lesinurad Impurity 4 Lesinurad M4 Metabolite 1-cyclopropylnaphthalene Lesinurad Impurity N lesinurad int N-(4-Cyclopropyl-1-naphthalenyl)-2-formylhydrazinecarbothioamide 3-bromo-4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione Lesinurad Impurity 5 Sodium Salt Lesinurad Impurity 10 Lesinurad Impurity K Methyl 2-(5-broMo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetate Lesinurad Impurity A Lesinurad Impurity 2 Lesinurad Impurity C1 4-cyclopropylnaphthalen-1-aMine hydrochloride Lesinurad Impurity L Lesinurad Impurity B

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