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| | N,N'-DICYCLOHEXYLUREA Basic information |
| | N,N'-DICYCLOHEXYLUREA Chemical Properties |
| Melting point | 232-233 °C(lit.) | | Boiling point | 408℃ | | density | 1.02 | | refractive index | 1.4832 (estimate) | | Fp | 158℃ | | storage temp. | 2-8°C | | solubility | DMSO (Slightly, Heated), Methanol (Slightly) | | pka | 13.89±0.20(Predicted) | | form | Liquid | | color | Clear | | Stability: | Hygroscopic | | InChIKey | ADFXKUOMJKEIND-UHFFFAOYSA-N | | CAS DataBase Reference | 2387-23-7(CAS DataBase Reference) | | EPA Substance Registry System | N,N'-Dicyclohexylurea (2387-23-7) |
| Hazard Codes | Xn,N | | Risk Statements | 22-51/53 | | Safety Statements | 61 | | WGK Germany | 3 | | TSCA | Yes | | HS Code | 29242100 |
| | N,N'-DICYCLOHEXYLUREA Usage And Synthesis |
| Chemical Properties | white crystalline powder | | Uses | N,N''-Dicyclohexylurea,is a substituted Urea (U822500) compound, which has shown to be a potent inhibitor of juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm M. sexta. Lomustine USP Related Compound C. | | Definition | ChEBI: 1,3-dicyclohexylurea is a member of ureas. | | Preparation | An excess of dry ice (200 g) was added gradually to a solution of dicyclohexylcarbodiimide (2.06 g, 0.01 mol), cyclohexylamine (1.98 g, 0.02 mol), and triethylamine (2.2 g, 0.02 mol) in THF at 75 ℃ over a period of 8 h. After stirring for 8 h, the reaction mixture was concentrated under reduced pressure and the resultant precipitate was collected. Fractional recrystallization of the precipitate from acetone/methanol gave N,N'-dicyclohexylurea; yield 2.2 g (98% based on dicyclohexylcarbodiimide and cyclohexylamine). | | Synthesis Reference(s) | The Journal of Organic Chemistry, 61, p. 4175, 1996 DOI: 10.1021/jo9522825 |
| | N,N'-DICYCLOHEXYLUREA Preparation Products And Raw materials |
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