Moroxydine hydrochloride

Moroxydine hydrochloride Basic information
Product Name:Moroxydine hydrochloride
Synonyms:1-morpholinocarbonimidoylguanidine hydrochloride;virustat;Moroxydine hydrochlorid;N-CarbaMiMidoylMorpholine-4-carboxiMidaMide hydrochloride;N-(aminoiminomethyl)-4-morpholinecarboximidamide,hydrochloride (1:1);MORPHOLINO-BIGUANIDE HYDROCHLORIDE;MORPHOLINO-BIUANIDE HYDROCHLORIDE;MOROXYDINE HCL
CAS:3160-91-6
MF:C6H14ClN5O
MW:207.66
EINECS:221-612-6
Product Categories:3160-91-6
Mol File:3160-91-6.mol
Moroxydine hydrochloride Structure
Moroxydine hydrochloride Chemical Properties
Melting point 211-214 °C(lit.)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO (Very Slightly, Heated), Water (Slightly)
form Solid
color Off-White
Merck 14,6272
InChIKeyFXYZDFSNBBOHTA-UHFFFAOYSA-N
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
WGK Germany 3
RTECS QD9815000
HS Code 2934.99.4700
MSDS Information
ProviderLanguage
SigmaAldrich English
Moroxydine hydrochloride Usage And Synthesis
OriginatorGrippe,Nissin
UsesMoroxydine hydrochloride is an antiviral used against a number of RNA and DNA viruses.
UsesMoroxydine is an antiviral used against a number of RNA and DNA viruses.
Manufacturing Process43.5 g morpholine, 41.7 ml concentrated hydrochloric acid, 40 ml of water, and 42 g dicyandiamide are refluxed for 48 hours, whereupon the reaction mixture is cooled to +5°C and filtered. The filtrate is evaporated to dryness and extracted and extracted with boiling ethanol. Yield: 50 g. The formed 4- morpholinecarboximidoylguanidine hydrochloride is purified by recrystallization from methanol. The salt may be converted into the base by adding equivalent of any basic compound (triethylamine, sodium bicarbonate and so on).
In practice it is usually used as hydrochloride.
Therapeutic FunctionAntiviral
General DescriptionDetermination of moroxydine hydrochloride in Gan Mao Qing capsules by derivative spectrophotometric signal multiplier method has been reported. Therapeutical efficiency of moroxidine hydrochloride against herpes virus induced keratoconjunctivitis has been evaluated by immunofluorescence techniques.
Moroxydine hydrochloride Preparation Products And Raw materials
Raw materialsMorpholine-->Dicyandiamide
1-(2-HYDROXYETHYL)GUANIDINE Biguanide N-((p-Chlorophenyl)amidino)-4-morpholinecarboxamidine hydrochloride MORPHOLINIUM CHLORIDE D-Glucosamine hydrochloride N-ETHYL-N-METHYLGUANIDINE Topotecan hydrochloride N,N-DIETHYL-GUANIDINE N-METHYLMORPHOLINE HYDROCHLORIDE Metformin hydrochloride 1.1-DIMETHYLGUANIDINE HYDROCHLORIDE Guanidine hydrochloride Hexamethyleneimine DIMETHYLGUANIDINE MORPHOLINE-4-CARBOXAMIDINE HEMISULFATE N,N-DIMETHYL-GUANIDINE Tridemorph 1-Methylguanidine hydrochloride

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