Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)-

Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Basic information
Product Name:Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)-
Synonyms:Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)-;6,7-dimethoxy-4-(4-nitrophenoxy)-Quinoline;Cabozantinib Genotoxic Impurity II;6,7-dimethoxy-4-(4-nitrophenoxy)quinolineQ: What is 6,7-dimethoxy-4-(4-nitrophenoxy)quinoline Q: What is the CAS Number of 6,7-dimethoxy-4-(4-nitrophenoxy)quinoline;Cabozantinib Nitro Analog
CAS:190728-24-6
MF:C17H14N2O5
MW:326.3
EINECS:
Product Categories:
Mol File:190728-24-6.mol
Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Structure
Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Chemical Properties
Boiling point 480.9±40.0 °C(Predicted)
density 1.319±0.06 g/cm3(Predicted)
pka4.33±0.30(Predicted)
Safety Information
MSDS Information
Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Usage And Synthesis
Uses6,7-Dimethoxy-4-(4-nitrophenoxy)quinoline is a related compound of cabozantinib (CAS# 849217-68-1) with potential anticancer activity. It can be used in the preparation of nicotinamide derivatives as Aurora kinase inhibitors, nquinolinyloxyphenylbenzenesulfonamides as AXL kinase inhibitors, N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas as vascular endothelial growth factor receptor 2 (VEGFR-2) tyrosine kinase inhibitors, and phenoxyquinolines as specific inhibitors of platelet-derived growth factor receptor tyrosine kinase.
Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Preparation Products And Raw materials
Cyclopropanecarboxylic acid, 1-[[(2-fluorophenyl)amino]carbonyl]- Cabozantinib impurity 1DYH 1,1-Cyclopropanedicarboxamide, N,N'-bis[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]- Cabozantinib Malate Cyclopropanecarboxylic acid, 1-[(phenylaMino)carbonyl]- 1,1-Cyclopropanedicarboxamide,N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-phenyl- Cyclopropanecarboxylic acid, 1-[[[4-[[7-methoxy-6-(sulfooxy)-4-quinolinyl]oxy]phenyl]amino]carbonyl]- 1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid Cabozantinib impurity DX2 Cabozantinib Impurity EXA 4-chloro-6,7-dimethoxyquinoline N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide Cabozantinib Impurity 5 4-Aminoveratrole

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