ChemicalBook Product Catalog API Antineoplastic agents Alkylating antineoplastic Nimustine hydrochloride

Nimustine hydrochloride

Nimustine hydrochloride Basic information
Product Name:Nimustine hydrochloride
Synonyms:1-(4-AMINO-2-METHYL-5-PYRIMIDINYL)-METHYL-3-(2-CHLOROETHYL)-3-NITROSOUREA HYDROCHLORIDE;ACNU;Nimustine HCl(ACNU);NIMUSTINE HCL;NIMUSTINE HYDROCHLORIDE;N'-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-N-(2-CHLOROETHYL)-N-NITROSOUREA HYDROCHLORIDE;1-(2-cloroetil)-1-nitroso-3-((2-metil-4-aminopirimidin-5-il)metil)ureaclorhi;1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosoureahydr
CAS:55661-38-6
MF:C9H14Cl2N6O2
MW:309.15
EINECS:678-313-2
Product Categories:Anti-cancer&immunity;Antitumors for Research and Experimental Use;Biochemistry
Mol File:55661-38-6.mol
Nimustine hydrochloride Structure
Nimustine hydrochloride Chemical Properties
Melting point 186°C(lit.)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility soluble in Methanol
form White to light yellow crystalline solid.
color White to Light yellow
PH3.0～4.5 (5g/l, 25℃)
Merck 14,6553
CAS DataBase Reference55661-38-6(CAS DataBase Reference)
Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 36/37/39-45
RIDADR UN 2811
RTECS YR8450000
HS Code 2933.59.8000
HazardClass 6.1
PackingGroup III
ToxicityLD50 in mice, rats (mg/kg): 62, 46 i.v. (Masuda)
MSDS Information
Nimustine hydrochloride Usage And Synthesis
UsesNimustine Hydrochloride is a DNA alkylator and cross-linking agent. It is used in chemotherapy in a part of anti-cancer cocktail used to treat malignant melanoma.
DefinitionChEBI: A hydrochloride obtained by combining nimustine with one equivalent of hydrochloric acid. An antineoplastic agent especially effective against malignant brain tumors.
Nimustine hydrochloride Preparation Products And Raw materials
Bendamustine hydrochloride Methyl Bendamustine Nimustine hydrochloride Bensulfuron methyl Topotecan hydrochloride Methoxyammonium chloride Sibutramine hydrochloride Tramadol hydrochloride Nimustine Kresoxim-methyl 1-AdaMantanethylaMine Thiophanate-methyl NITROSOGUANIDINE Diphenhydramine Hydrochloride Predmustine METHYL THIOPHENE-2-CARBOXYLATE N-Nitrocarbamide
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