DL-Adrenalin

DL-Adrenalin Basic information
Product Name:DL-Adrenalin
Synonyms:dl-adrenalin;(+/-)-EPINEPHRINE;(+/-)-ADRENALIN;4-[1-HYDROXY-2-(METHYLAMINO)ETHYL]-1,2-BENZENEDIOL;4-(1-HYDROXY-2-METHYLAMINO-ETHYL)-BENZENE-1,2-DIOL;1-(3,4-dihydroxyphenyl)-2-(methylamino)ethanol;3,4-DIHYDROXY-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL;3,4-dihydroxy-1-[1-hydroxy-2-(methylamino)-ethyl]benzene
CAS:329-65-7
MF:C9H13NO3
MW:183.2
EINECS:206-347-6
Product Categories:Amines;Aromatics;Neurochemicals;Standards - 13C & 2H for GC-Mass Spectrometry
Mol File:329-65-7.mol
DL-Adrenalin Structure
DL-Adrenalin Chemical Properties
Melting point 197 °C (dec.)(lit.)
Boiling point 316.88°C (rough estimate)
alpha -0.5~+0.5°(D/20)(c=1,0.1mol/l HCl)
density 1.1967 (rough estimate)
refractive index 1.4760 (estimate)
storage temp. 2-8°C
solubility 0.1 M HCL : 2.5 mg/mL (13.65 mM; ultrasonic and adjust pH to 1 with HCl)DMSO : 1 mg/mL (5.46 mM; ultrasonic and adjust pH to 7 with HCl)Ethanol : < 1 mg/mL (insoluble)H2O : < 0.1 mg/mL (insoluble)
form Powder
pka9.60±0.10(Predicted)
Water Solubility Sparingly soluble
Sensitive Light Sensitive
Merck 14,3619
CAS DataBase Reference329-65-7(CAS DataBase Reference)
EPA Substance Registry System4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol (329-65-7)
Safety Information
Hazard Codes T
Risk Statements 24-36/37/38
Safety Statements 26-36/37-45
RIDADR UN 2811 6.1/PG 2
WGK Germany 3
RTECS DO2975000
HazardClass 6.1(b)
PackingGroup III
MSDS Information
DL-Adrenalin Usage And Synthesis
Chemical PropertiesSolid
UsesA hormone and neurotransmitter
UsesEndogenous catcholamine with combined α-and β-agonist activity. Principal sympathomimetic hormone produced by the adrenal medulla. Bronchodilator; cardiostimulant; mydriatic; antiglaucoma.
UsesDL-Adrenaline is a hormone and a neurotransmitter secreted by the medulla of the adrenal glands. In medicine DL-Adrenaline is used chiefly as a stimulant in cardiac arrest, as a vasoconstrictor in shock, and as a bronchodilator and antispasmodic in bronch
DefinitionChEBI: A catecholamine in which the aminoethyl side-chain is hydroxy-substituted at C-1 and methylated on nitrogen.
Brand nameVaponefrin (Fisons).
General DescriptionOdorless light brown or nearly white crystals.
Air & Water ReactionsSlightly water soluble .
Reactivity ProfileLight sensitive. Incompatible with heat, air, iron salts, and alkalis. . An aminoalcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Incompatible with heat, air, iron salts, and alkalis. .
Health HazardSYMPTOMS: Pallor, tremor, anxiety, nervousness, rapid, forceful pulse, rise in blood pressure and temperature, rapid breathing, dilation of the pupils.
Fire HazardFlash point data for DL-Adrenalin are not available, however, DL-Adrenalin is probably combustible.
DL-Adrenalin Preparation Products And Raw materials
Preparation ProductsL(-)-Epinephrine
Norepinephrine Impurity 23 Norepinephrine Impurity 17 HCl (rac-Norepinephrine HCl) Norepinephrine Impurity 2 Norepinephrine Impurity 15 Norepinephrine Impurity 24 HCl Norepinephrine Impurity 18 HCl Norepinephrine Impurity 27 3-(2-amino-1-hydroxyethyl)benzene-1,2-diol 3,4-Dihydroxyacetophenone 4-(2-Chloro-1-hydroxyethyl)-1,2-benzenediol Norepinephrine Impurity 26 HCl 2-chloro-2-5-dihydroxyacetophenone 1-(3,4-DIHYDROXYPHENYL)-2-(METHYLAMINO)ETHANOL-(+)-BITARTRATE 1-(3,4-DIHYDROXYPHENYL)-2-(METHYLAMINO)ETHANOL-(+)-BITARTRATE (+)-Bicuculline Epinephrine Hydrochloride CHLOROPHOSPHONAZO III Racanisodamine

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