ChemicalBook Product Catalog Biochemical Engineering Inhibitors Cell Cycle Rho inhibitor 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one

1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one

1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Basic information
Product Name:1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one
Synonyms:1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one;2-Propen-1-one, 1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)aMino]acetyl]-1-piperazinyl]-;K-Ras G12C-IN-12;105456;CS-1676;G12C INHIBITOR 12;K RAS INHIBITOR 12;K RAS INHIBITOR 12; G12C INHIBITOR 12
CAS:1469337-95-8
MF:C15H17ClIN3O3
MW:449.67
EINECS:
Product Categories:Inhibitors
Mol File:1469337-95-8.mol
1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Structure
1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Chemical Properties
Boiling point 680.2±55.0 °C(Predicted)
density 1.736±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility ≥8.98 mg/mL in DMSO with gentle warming
form solid
pka8.60±0.50(Predicted)
Safety Information
MSDS Information
1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Usage And Synthesis
references[1]. ostrem jm1, peters u, sos ml, et al. k-ras(g12c) inhibitors allosterically control gtp affinity and effector interactions. nature, 2013, 503(7477): 548-551.
1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Preparation Products And Raw materials
Olaparib CHIR-99021 lysyllysine K-Ras(G12C) inhibitor 6 K-Ras(G12C) inhibitor 9 K-Ras inhibitor Everolimus
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