Sunitinib N-Oxide

Sunitinib N-Oxide Basic information
Product Name:Sunitinib N-Oxide
Synonyms:Sunitinib N-Oxide;DNCVCKYIYMUMFC-ATVHPVEESA-N;(Z)-N,N-diethyl-2-(5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethanamine oxide;Sunitinib Impurity 6;1H-?Pyrrole-?3-?carboxamide, N-?[2-?(diethyloxidoamino)?ethyl]?-?5-?[(Z)?-?(5-?fluoro-?1,?2-?dihydro-?2-?oxo-?3H-?indol-?3-?ylidene)?methyl]?-?2,?4-?dimethyl;Sunitinib N-O;Sunitinib N-oxide/(Z)-N,N-Diethyl-2-(5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethan-1-amine oxide;(Z)-N,N-diethyl-2-(5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethan-1-amine oxide
CAS:356068-99-0
MF:C22H27FN4O3
MW:414.47
EINECS:
Product Categories:
Mol File:356068-99-0.mol
Sunitinib N-Oxide Structure
Sunitinib N-Oxide Chemical Properties
Melting point >155°C (dec.)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka11.69±0.20(Predicted)
form Solid
color Yellow to Dark Orange
Stability:Hygroscopic
Safety Information
MSDS Information
Sunitinib N-Oxide Usage And Synthesis
UsesSunitinib N-Oxide, is a derivative of Sunitinib (S820000), a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK), used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor. It is a COVID19-related research product.
Sunitinib N-Oxide Preparation Products And Raw materials
5-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid N-(2-(Diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide Ethyl 2,4-dimethyl-1H-pyrrole-3-carboxylate Sunitinib Malate Sunitinib iMpurity Sunitinib Impurity B Pyrrole-2,4-dicarboxaldehyde, 3,5-dimethyl- (6CI,7CI,8CI) Sugammadex sodium 5-Fluoro-2-oxindole Sunitinib Impurity 1 Ethyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate Sunitinib Impurity 9 2,4-DIMETHYL PYRROL-3-CARBALDEHYDE Sunitinib Impurity 2 Sunitinib Impurity 7 (Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)Methyl)-2,4-diMethyl-1H-pyrrole-3-carboxaMide De-5-fluoro 4-FluorochidaMide Sunitinib

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