ChemicalBook Product Catalog Biochemical Engineering Inhibitors PI3K / Akt / mTOR Akt inhibitors GSK-2110183C

GSK-2110183C

GSK-2110183C Basic information
Product Name:GSK-2110183C
Synonyms:Afuresertib(GSK2110183C);Afuresertib;GSK 2110183C;GSK2110183C;GSK-2110183C;N-((S)-1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide;Afuresertib, GSK-2110183, GSK-2110183B;Delitinib
CAS:1047644-62-1
MF:C18H17Cl2FN4OS
MW:427.32
EINECS:1592732-453-0
Product Categories:Inhibitors
Mol File:1047644-62-1.mol
GSK-2110183C Structure
GSK-2110183C Chemical Properties
Boiling point 535.1±50.0 °C(Predicted)
density 1.49±0.1 g/cm3(Predicted)
storage temp. Store at -20°C, protect from light, stored under nitrogen
solubility DMSO:62.5(Max Conc. mg/mL);146.26(Max Conc. mM)
Ethanol:85.0(Max Conc. mg/mL);198.91(Max Conc. mM)
form Powder
pka13.03±0.46(Predicted)
Safety Information
MSDS Information
GSK-2110183C Usage And Synthesis
UsesAfuresertib is a potent pan-AKT inhibitor that demonstrated synergy with bortezomib in preclinical models of multiple myeloma.
DefinitionChEBI: N-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methyl-3-pyrazolyl)-2-thiophenecarboxamide is a member of amphetamines.
GSK-2110183C Preparation Products And Raw materials
Veliparib 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Panobinostat (+)-JQ1 3-Chloro-2-methylpropene
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