4-Difluoromethoxy-3-hydroxybenzaldehyde

4-Difluoromethoxy-3-hydroxybenzaldehyde Basic information
Product Name:4-Difluoromethoxy-3-hydroxybenzaldehyde
Synonyms:2-(Difluoromethoxy)-5-formylphenol, alpha,alpha-Difluoro-4-formyl-2-hydroxyanisole;Benzaldehyde,4-(difluoroMethoxy)-3-hydroxy-;Roflumilast impurity 19;3-Hydroxy-4-diflouromethylbenzaldehyde;4-(Difluoromethoxy)-3-hydroxybenzaldehyde 97%;4-(Difluoromethoxy)-3-hydroxybenzaldehyde97%;3-hydroxy-4-difluoroMethoxy benzaldehyde;4-DIFLUOROMETHOXY-3-HYDROXYBENZALDEHYDE
CAS:151103-08-1
MF:C8H6F2O3
MW:188.13
EINECS:687-745-0
Product Categories:Roflumilast interemdiate;Aromatics;Aldehydes;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het;Intermediates;Intermediate
Mol File:151103-08-1.mol
4-Difluoromethoxy-3-hydroxybenzaldehyde Structure
4-Difluoromethoxy-3-hydroxybenzaldehyde Chemical Properties
Melting point 85-90°C
Boiling point 280.6±35.0 °C(Predicted)
density 1.395±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka7.85±0.35(Predicted)
color White
InChIInChI=1S/C8H6F2O3/c9-8(10)13-7-2-1-5(4-11)3-6(7)12/h1-4,8,12H
InChIKeyZLIKNROJGXXNJG-UHFFFAOYSA-N
SMILESC(=O)C1=CC=C(OC(F)F)C(O)=C1
CAS DataBase Reference151103-08-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-51-22
Safety Statements 26-36/37/39
WGK Germany 3
Hazard Note Irritant
HS Code 2913000090
MSDS Information
4-Difluoromethoxy-3-hydroxybenzaldehyde Usage And Synthesis
Chemical Properties4-Difluoromethoxy-3-hydroxybenzaldehyde is white powder
Uses4-Difluoromethoxy-3-hydroxybenzaldehyde is a phenyl alkyl ketone derivative used in the preparation of phosphodiesterase-4 (PDE4) inhibitors.
4-DIFLUOROMETHOXY-3-METHOXY-BENZOIC ACID HYDRAZIDE 4-DIFLUOROMETHOXY-3-ETHOXY-BENZOIC ACID 4-Difluoromethoxy-3-hydroxybenzaldehyde 4-(Trifluoromethoxy)aniline 4-DIFLUOROMETHOXY-3-METHOXY-BENZOIC ACID METHYL ESTER 2,2-Difluorobenzodioxole-5-carboxaldehyde 4-(Difluoromethoxy)-3-methoxybenzamide 2,4-Dihydroxybenzaldehyde (Trifluoromethoxy)benzene 4-(Trifluoromethyl)benzaldehyde Benzaldehyde Veratraldehyde Roflumilast p-Anisaldehyde Protocatechualdehyde 2,2-Difluoro-1,3-benzodioxole-5-carbonyl chloride 4-Ethyl-5-fluoro-6-hydroxypyrimidine 1-(4-DIFLUOROMETHOXY-3-METHOXY-PHENYL)-4,4,4-TRIFLUORO-BUTANE-1,3-DIONE

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