ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Amino alcohol derivative (1R,2S)-1-Amino-2-indanol

(1R,2S)-1-Amino-2-indanol

(1R,2S)-1-Amino-2-indanol Basic information
Uses
Product Name:(1R,2S)-1-Amino-2-indanol
Synonyms:(1R,2S)-(+)-cis-1-Amino-2-indanol,98%;1H-Inden-2-ol, 1-amino-2,3-dihydro-, (1R,2S)-;(1R,2S)-(+)-cis-1-Amino-2-indanol ,99%;(1R,2S)-1-Aminoindan-2-ol, (1R,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol;(1R,2S)-(+)-cis-1-AMino-2-indanol, 98% 1GR;2S)-1-AMino-2-indanol;(1R,2S)-1-Aminoindan-2-ol, (1R,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol, (1R,2S)-2-Hydroxyindan-1-amine;(1R,2S)-(+)-cis-1-AMino-2-indanol 99%
CAS:136030-00-7
MF:C9H11NO
MW:149.19
EINECS:603-940-5
Product Categories:CHIRAL COMPOUNDS;organic alcohol;Amino Alcohols (Chiral);Chiral Building Blocks;Synthetic Organic Chemistry;CHIRAL CHEMICALS;Chiral Nitrogen;chiral;API intermediates
Mol File:136030-00-7.mol
(1R,2S)-1-Amino-2-indanol Structure
(1R,2S)-1-Amino-2-indanol Chemical Properties
Melting point 118-121 °C(lit.)
alpha 44.5 º (c=1, methanol)
Boiling point 270.27°C (rough estimate)
density 1.0753 (rough estimate)
refractive index 43 ° (C=1, MeOH)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility soluble in Methanol
pka14.79±0.40(Predicted)
form Powder
color White to light beige
optical activity[α]22/D +63°, c = 0.2 in chloroform
Water Solubility soluble
BRN 2803743
CAS DataBase Reference136030-00-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-20/21/22
Safety Statements 26-36-36/37/39
RIDADR 2811
WGK Germany 3
F 10-23
TSCA No
HS Code 29061990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
(1R,2S)-1-Amino-2-indanol Usage And Synthesis
Uses(1R,2S)-1-Amino-2-indanol  Class of catalytic ligands which when used with a reducing agent, exhibit enantioselectivity in the reduction of a wide range of substrates.
Chemical Properties(1R,2S)-1-Amino-2-indanol is white to light yellow crystal powder
UsesThis cis-aminoindanol and its antipode have been used in the preparation of a series of potent HIV-1 protease inhibitory peptides. Also, they have served as chiral ligands in the catalytic asymmetric reduction of prochiral ketones with boranes.
(1R,2S)-1-Amino-2-indanol Preparation Products And Raw materials
Preparation ProductsAcetamide, N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)--->(3aR,8aS)-2-[2-(diphenylphosphino)phenyl]-3a,8a-dihydro-8H-Indeno[1,2-d]oxazole-->(3aR,8aS)-2-(pyridin-2-yl)-8,8a-dihydro-3aH-indeno[1,2-d]oxazole
FMOC-(1R,2S)-(+)-CIS-1-AMINO-2-INDANOL,FMOC-(1R,2S)-(+)-CIS-1-AMINO-2-INDANOL indanol (1r,2s)-1-[(3,5-di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol CIS-2-AMINO-1-INDANOL,CIS-2-AMINO-1-INDANOL (1S,2S)-1-Amino-2-indanol ACETAMINOPHENOL BP/USP 2,6-BIS((3AR,8AS)-8H-INDENO(1,2-D)OXAZO& (1R,2S)-1-Amino-2-indanol EC 2.6.1.2 (5AS, 10BR)-(-)-5A,10B-DIHYDRO-2-(PENTAFLUOROPHENYL)-4H,6H-INDENO[2,1-B][1,2,4]TRIZOLO[4,3-D][1,4]OXAZINIUM TETRAFLUOROBORATE ALTRENOGEST 4-Amino-benzenesulfonic acid monosodium salt BOC-(1R,2S)-(+)-CIS-1-AMINO-2-INDANOL,(1R,2S)-N-BOC-1-AMINO-2-INDANOL,BOC-(1R,2S)-(+)-CIS-1-AMINO-2-INDANOL (3AR-CIS)-(+)-3,3A,8,8A-TETRAHYDRO-2H-INDENO[1,2-D]OXAZOL-2-ONE (+)-2,2'-METHYLENEBIS[(3AR,8AS)-3A,8A-DIHYDRO-8H-INDENO[1,2-D]OXAZOLE] [3AR-[2(3'A R*,8'A S*),3'A-BETA,8'A-BETA]]-(+)-2,2'-METHYLENEBIS[3A,8A-DIHYDRO-8 H-INDENO[1,2-D]OXAZOLE] AMINO ACIDS (S)-CIS-1-AMINO-2-INDANOL,(S)-CIS-1-AMINO-2-INDANOL,CIS-1-AMINO-2-INDANOL,CIS-1-AMINO-2-INDANOL
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