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| | 1-Bromo-9H-carbazole Basic information |
| Product Name: | 1-Bromo-9H-carbazole | | Synonyms: | 1-broMocarbazole;-broMo-9H-carbazole;1-broMo-9H-carbazole;9H-Carbazole, 1-broMo-;1-bromo-9H-carbozle;1-Bromocarbazole >;-broMo-9H-carbazole | | CAS: | 16807-11-7 | | MF: | C12H8BrN | | MW: | 246.1 | | EINECS: | | | Product Categories: | | | Mol File: | 16807-11-7.mol |  |
| | 1-Bromo-9H-carbazole Chemical Properties |
| Melting point | 123-124℃ (acetic acid ) | | Boiling point | 409.2±18.0 °C(Predicted) | | density | 1.617±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | form | powder to crystal | | pka | 16.14±0.30(Predicted) | | color | White to Light yellow |
| | 1-Bromo-9H-carbazole Usage And Synthesis |
| Chemical Properties | White to yellow powder or crystals. | | Uses | 1-Bromo-9H-carbazole is a useful research chemical, mainly used as a pharmaceutical intermediate and an intermediate in organic synthesis. | | Preparation | A 1-Bromo-9H-carbazole is synthesized as follows：Under noble gas protection, by 3,6- bis- Tert-butyl carbazole is dissolved in 1,2- dichloroethanes, adds hydrobromic acid, controlling reaction temperature to be slowly added dropwise hydrogen peroxide, dropping is completely Overnight, reactant liquor is washed, and separates organic layer for natural temperature reaction, is dried, and adds methyl alcohol dispersion, obtains the tertiary fourth of bromo- 3, the 6- of 1- bis- Base carbazole；Then 1- bromo- 3,6- di-t-butyl carbazole and isopropanol solvent are added in reaction bulb, controlling reaction temperature slowly adds Enter alchlor reaction, add water after terminating terminating reaction, through extraction, organic layer sodium hydrate aqueous solution is washed, and is dried overnight, concentrate Obtain crude product, methylene chloride-methanol mixed solvent is recrystallized to give product 1-Bromo-9H-carbazole.
Production method of 1-bromocarbazole
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| | 1-Bromo-9H-carbazole Preparation Products And Raw materials |
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