ChemicalBook Product Catalog Organic Chemistry Organic fluorine compound Fluoroaniline series Gefitinib InterMediate B

Gefitinib InterMediate B

Gefitinib InterMediate B Basic information
Product Name:Gefitinib InterMediate B
Synonyms:N-(3-chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-Methoxyquinazolin-4-aMine;Gefitinib InterMediate B;6-(3-chloropropoxy)-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazolin-4-ylamine;4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxy-;Gefitinib InterMediate B ISO 9001：2015 REACH;N-(3-Chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxy-4-quinazolinamine
CAS:912556-91-3
MF:C18H16Cl2FN3O2
MW:396.24
EINECS:
Product Categories:
Mol File:912556-91-3.mol
Gefitinib InterMediate B Structure
Gefitinib InterMediate B Chemical Properties
Melting point 234-236 °C
Boiling point 523.3±50.0 °C(Predicted)
density 1.392±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka5.40±0.30(Predicted)
Safety Information
MSDS Information
Gefitinib InterMediate B Usage And Synthesis
Uses4-Chloro-6-(3-chloropropoxy)-7-methoxyquinazoline is an analogue of Gefitinib, an inhibitor of EGFR with anti-tumor activity.
3-(3-morpholinylpropoxy)-4-methoxybenzonitrile Benzaldehyde, 2-amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]- 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate 4-Defluoro-4-hydroxy Gefitinib Gefitinib Impurity 14 N-(3-chloro-4-fluorophenyl)-6 ,7-dimethoxyquinazolin-4-amine N'-(4-Amino-2-cyanophenyl)-N,N-dimethylformamidine 3(2H)-Benzofuranone, 6-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-4-methoxy-5-methyl- 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 3-DesMorpholinyl-3-hydroxyethylaMino Gefitinib Gefitinib iMpurity 3,4-Dichloro Gefitinib 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol Gefitinib InterMediate A 6,7-Dimethoxy-3,4-dihydroquinazoline-4-one N-(3-chloro-4-fluorophenyl)-7 -methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)quinazolin-4-amine Desfluoro Impurity 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
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