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Insulin-like Growth Factor-1 Receptor Inhibitor

Insulin-like Growth Factor-1 Receptor Inhibitor Basic information
Product Name:Insulin-like Growth Factor-1 Receptor Inhibitor
Synonyms:4-[[(2S)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]-3-[7-methyl-5-(4-morpholinyl)-1H-benzimidazol-2-yl]-2(1H)-pyridinone;CS-469;BMS 536924;BMS536924;BMS-536924;Insulin-like Growth Factor-1 Receptor Inhibitor;4-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-3-[4-methyl-6-(4-morpholinyl)-1H-benzimidazol-2-yl]- 2(1H)-pyridinone;CS-0117;HY-10262
CAS:468740-43-4
MF:C25H26ClN5O3
MW:479.96
EINECS:
Product Categories:Inhibitors
Mol File:468740-43-4.mol
Insulin-like Growth Factor-1 Receptor Inhibitor Structure
Insulin-like Growth Factor-1 Receptor Inhibitor Chemical Properties
Melting point >206°C (dec.)
density 1.44
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility DMSO (Slightly)
pka10.40±0.10(Predicted)
form Solid
color Light Yellow to Yellow
CAS DataBase Reference468740-43-4
Safety Information
MSDS Information
Insulin-like Growth Factor-1 Receptor Inhibitor Usage And Synthesis
UsesBMS 536924 is an inhibitor of insulin-like growth factor receptor (IGF1R) kinase and insulin receptor. BMS 536924 was reported to have antitumor activity.
DefinitionChEBI: 4-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-3-[4-methyl-6-(4-morpholinyl)-1,3-dihydrobenzimidazol-2-ylidene]-2-pyridinone is a member of benzimidazoles.
storageStore at -20°C
Insulin-like Growth Factor-1 Receptor Inhibitor Preparation Products And Raw materials
Doxorubicin hydrochloride Olaparib BMS-754807 Inositol Corticotropin Crizotinib Flavopiridol (Alvocidib) HCl Insulin-Like Growth Factor I (IGF1) Α-PROTEIN Calcitonin TSH Testosterone IGF-1 Linsitinib Glucagon Aspartate aminotransferase Creatinine Hydrocortisone
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