DIETHYL BENZYLIDENEMALONATE

DIETHYL BENZYLIDENEMALONATE Basic information
Product Name:DIETHYL BENZYLIDENEMALONATE
Synonyms:BENZALMALONIC ACID DIETHYL ESTER;BENZALMALONIC ACID ETHYL ESTER;BENZYLIDENEMALONIC ACID DIETHYL ESTER;DIETHYL BENZYLIDENEMALONATE;DIETHYL BENZALMALONATE;2-Benzylidene-malonic acid diethyl ester;2-Benzylidene-malonicaciddiethylester;b,b-Diethoxycarbonylstyrene
CAS:5292-53-5
MF:C14H16O4
MW:248.27
EINECS:226-137-8
Product Categories:
Mol File:5292-53-5.mol
DIETHYL BENZYLIDENEMALONATE Structure
DIETHYL BENZYLIDENEMALONATE Chemical Properties
Melting point 28-31°C
Boiling point 215-217 °C/30 mmHg (lit.)
density 1.107 g/mL at 25 °C (lit.)
refractive index n20/D 1.536(lit.)
Fp >230 °F
storage temp. Sealed in dry,Room Temperature
form clear liquid
color Colorless to Yellow
Water Solubility Insoluble in water.
BRN 528894
CAS DataBase Reference5292-53-5(CAS DataBase Reference)
Safety Information
Safety Statements 23-24/25
WGK Germany 3
HS Code 29173990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
DIETHYL BENZYLIDENEMALONATE Usage And Synthesis
UsesDiethyl benzylidenemalonate is used as a pharmaceutical intermediate. It is also involved in the Conjugate addition of cyanide ion to arylidenemalonic esters provides a useful route to arylsuccinic acids.
Synthesis Reference(s)Organic Syntheses, Coll. Vol. 3, p. 377, 1955
Tetrahedron Letters, 33, p. 7535, 1992 DOI: 10.1016/S0040-4039(00)60817-1
DIETHYL BENZYLIDENEMALONATE Preparation Products And Raw materials
Raw materialsBenzaldehyde-->Diethyl malonate-->Piperidine
Preparation Products2-Cyanobenzenepropanoic Acid Ethyl Ester-->1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester
2-[3,5-DIAMINO-4-(4-METHOXY-PHENOXY)-BENZYLIDENE]-MALONIC ACID DIETHYL ESTER PROPANEDIOIC ACID, [(4-HYDROXY-3,5-DIMETHOXYPHENYL)METHYLENE]-, DIETHYL ESTER DIETHYL 2-[(4-FLUOROPHENYL)METHYLENE]MALONATE DIETHYL 2-[2-TRIFLUOROMETHYL-4H-CHROMENE-4-YLIDENE]MALONATE DIETHYL BENZYLIDENEMALONATE Benzylmalonic acid AKOS BC-1761 2-[3,5-DIIODO-4-(4-METHOXY-PHENOXY)-BENZYLIDENE]-MALONIC ACID DIETHYL ESTER 2-(4-HYDROXY-BENZYLIDENE)-MALONIC ACID DIETHYL ESTER 2-[4-(4-METHOXY-PHENOXY)-3,5-DINITRO-BENZYLIDENE]-MALONIC ACID DIETHYL ESTER Diethyl methylmalonate Diethyl 4-methoxybenzalmalonate DIETHYL BENZYLIDENEMALONATE, (DIETHYL BENZALMALONATE) DIETHYL 2-[(4-METHYLPHENYL)METHYLENEMALONATE] DIETHYL 2-[(4-CHLOROPHENYL)METHYLENE]MALONATE Malonic acid

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