(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate

(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Basic information
Product Name:(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
Synonyms:(4R,CIS)-1,1-DIMETHYLETHYL-6-AMINOETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;(4R-Cis)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxoane-4-acetate;(4R,6R)-TERT-BUTYL-6-(2-AMINOETHYL)-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;(4R-CIS)-1,1-DIMETHYLETHYL-6-AMINOETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE (ATS-9);Atorvastatin Intermediate Ⅰ;Atorvastatin Intermediate 1;ATROVASTATIN INTERMEDIATES;(4R-Cia)-1,1-dimethyl ethyl-6-cyano methyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:125995-13-3
MF:C14H27NO4
MW:273.37
EINECS:603-112-3
Product Categories:Amines;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;INTERMEDIATESOFATORVASTATIN;chiral;ATORVASTATIN CALCIUM;(intermediate of atorvastatin)
Mol File:125995-13-3.mol
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Structure
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Chemical Properties
Boiling point 339.8±17.0 °C(Predicted)
density 0.992±0.06 g/cm3(Predicted)
refractive index 1.454-1.456
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Chloroform
pka9.80±0.10(Predicted)
form Viscous Liquid
color Light yellow to green or light blue
λmax204nm(EtOH)(lit.)
InChIKeyHWSHVKNLMBMKSR-GHMZBOCLSA-N
CAS DataBase Reference125995-13-3(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
HS Code 29153900
MSDS Information
ProviderLanguage
ACROS English
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Usage And Synthesis
Description(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate is an impurity of Atorvastatin. Atorvastatin is a drug used to lower cholesterol levels in the blood. It belongs to a class of drugs called HMG-CoA reductase inhibitors, and it works by blocking an enzyme that plays a role in the production of cholesterol.
Chemical PropertiesColorless to light yellow liqui
UsesAn impurity of Atorvastatin (A791750).
Uses(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate is an useful synthetic intermediate.
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Preparation Products And Raw materials
Dimethylbenzylcarbinyl acetate Dacthal (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate 1,2-Dioxane (S)-2,2-DIMETHYL-4-AMINOMETHYL-1,3-DIOXANE tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate Methyl 2,2-dimethylphenylacetate Ortho-Hydroxy atorvastatin calcium salt Atorvastatin Oxirane Impurity O-Methyl Atorvastatin Calcium Salt 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt Atorvastatin Dehydro Lactone 2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide Difluoro Atorvastatin Acetonide tert-Butyl Ester Atorvastatin Impurity 15 Atorvastatin Impurity 31 3-Oxo Atorvastatin tert-Butyl Ester Atorvastatin

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