N-ME-TYR-OH

N-ME-TYR-OH Basic information
Product Name:N-ME-TYR-OH
Synonyms:H-METYR-OH;H-L-METYR-OH HCL;N-METHYL-L-TYROSINE;N-METHYL-L-TYROSINE HYDROCHLORIDE;N-ME-TYR-OH;N-ME-TYR-OH HCL;N-ME-TYROSINE;N-ALPHA-METHYL-L-TYROSINE HYDROCHLORIDE
CAS:537-49-5
MF:C10H13NO3
MW:195.22
EINECS:208-670-8
Product Categories:amino acids;Aromatics;Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Chiral Reagents;amino acid
Mol File:537-49-5.mol
N-ME-TYR-OH Structure
N-ME-TYR-OH Chemical Properties
Melting point 253-256°C (dec.)
alpha D21 +19.6° (c = 3.8 in 10% HCl)
Boiling point 331.88°C (rough estimate)
density 1.1926 (rough estimate)
refractive index 1.5150 (estimate)
storage temp. Store at RT.
solubility Aqueous Acid (Slightly), Aqueous Base (Slightly)
pka2.27±0.16(Predicted)
form Solid
color White to Off-White
optical activity[α]/D +16.0±1.0°, c = 1 in 1 M HCl
BRN 2646795
Stability:Hygroscopic
Safety Information
Hazard Codes Xi
Risk Statements 36-38
Safety Statements 26
WGK Germany 3
MSDS Information
N-ME-TYR-OH Usage And Synthesis
Chemical PropertiesWhite to Off-White Solid
UsesN-Methyl-L-tyrosine is a tyrosine hydroxylase inhibitor. An antihypertensive in pheochromocytoma. N-Methyl-L-tyrosine from seeds of Combretum zeyheri.
N-ME-TYR-OH Preparation Products And Raw materials
Raw materials(S)-2-(((benzyloxy)carbonyl)(Methyl)aMino)-3-(4-hydroxyphenyl)propanoic acid-->Z-TYR-OH-->N-Me-D-Tyr-OH-->Methyl L-tyrosinate-->Formaldehyde
Preparation ProductsL-Valine-->L-Alanine
BOC-N-ME-TYR(2,6-DICHLORO-BZL)-OH H-GLY-TYR-OET HCL CHLOROAC-TYR-OET N-FORMYL-L-TYROSINE H-ALA-TYR-OET HCL Z-TYR-TYR-OH BOC-L-TYROSINE 2,4,5-TRICHLOROPHENYL ESTER BOC-3,5-DIIODO-TYR(3'-BROMO-BZL)-OH AC-3,5-DINITRO-TYR-OET Ethyl N-benzoyl-L-tyrosinate H-PRO-GLN-PHE-TYR-OH HCL N-Acetyl-3,5-diiodo-L-tyrosine N-Acetyl-3,5-dinitro-L-tyrosine Z-TYR(Z)-OH BOC-O-BENZYL-L-TYROSINE 4-NITROPHENYL ESTER Z-TYR-ONP CHLOROACETYL-L-TYROSINE BOC-3,5-DIIODO-TYR(2',6'-DICHLORO-BZL)-OH

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