ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Hydroxypyridine 2-Chloro-3-hydroxypyridine

2-Chloro-3-hydroxypyridine

2-Chloro-3-hydroxypyridine Basic information
Product Name:2-Chloro-3-hydroxypyridine
Synonyms:2-Chloro-3-hydroxypyridine≥ 99% (HPLC);2-CHLORO-PYRIDINE-3-OL;2-CHLOROPYRIDIN-3-OL;2-CHLORO-3-HYDROXYPYRIDINE;2-CHLORO-3-PYRIDINOL;2-CHLORO-3-HYDROXYPYRIDINE 2-CHLORO-PYRIDIN-3-OL;2-CHLORO-3-HYDROXYPYRIDINE (2-CHLORO-3-PYRIDINOL);2-chloro-3-pyridino
CAS:6636-78-8
MF:C5H4ClNO
MW:129.54
EINECS:229-635-3
Product Categories:Chloropyridines;Halopyridines;PYRIDINE;Pyridines, Pyrimidines, Purines and Pteredines;Halides;Pyridines;Pyridines derivatives;Imidazoles
Mol File:6636-78-8.mol
2-Chloro-3-hydroxypyridine Structure
2-Chloro-3-hydroxypyridine Chemical Properties
Melting point 170-172 °C (lit.)
Boiling point 316.2±22.0 °C(Predicted)
density 1.2309 (rough estimate)
refractive index 1.4510 (estimate)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka4.32±0.10(Predicted)
form Powder
color Light beige
BRN 2216
InChIKeyRSOPTYAZDFSMTN-UHFFFAOYSA-N
CAS DataBase Reference6636-78-8(CAS DataBase Reference)
NIST Chemistry Reference2-Chloro-3-pyridinol(6636-78-8)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-20/21/22
Safety Statements 26-37/39-24/25-36
WGK Germany 3
RTECS UU7707000
HazardClass IRRITANT
HS Code 29333990
MSDS Information
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2-Chloro-3-hydroxypyridine English
SigmaAldrich English
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ALFA English
2-Chloro-3-hydroxypyridine Usage And Synthesis
Chemical Propertieslight beige powder
Uses2-Chloro-3-hydroxypyridine has been used in the preparation of 3-hydroxypyridine-2( 1 H)-selone. It has also been used in the synthesis of all four possible benzo[4,5]furopyridine tricyclic heterocycles: benzo[4,5]furo[2,3-b]pyridine, benzo[4,5]furo[2,3-c]pyridine, benzo[4,5]furo[3,2-c]pyridine, and benzo[4,5]furo[3,2-b]pyridine. the synthesis involves α and γ-activation of chloropyridines, as well as palladium-mediated reactions.
2-Chloro-3-hydroxypyridine Preparation Products And Raw materials
Preparation Products2,3-Dimethoxypyridine-->2-Chloro-5-hydroxypyridine-->2,3-Dihydroxypyridine-->2-Chloro-3-methoxypyridine-->2-Chloro-3-(oxiran-2-ylmethoxy)pyridine-->2-Chloro-3-Methoxypyridine-4-carboxaldehyde-->2-(2-Hydroxyethoxy)pyridin-3-ol
2-CHLORO-3-PYRIDYL 2-CHLORONICOTINATE 2-CHLORO-3-BENZYLOXYMETHYLPYRIDINE 2-Chloro-3-hydroxy-4-pyridinecarboxylicacidmethylester 2-Chloro-3-hydroxypyridine 2-CHLORO-3-PYRIDYL BENZO[B]THIOPHENE-2-CARBOXYLATE 2-CHLORO-3-PYRIDYL THIOPHENE-2-CARBOXYLATE 2-CHLORO-3,4-DIMETHOXYPYRIDINE HYDROCHLORIDE 2-CHLORO-3-PYRIDYL 4-METHYLBENZENE-1-SULFONATE 2-CHLORO-3-PYRIDYL 4-CHLOROBENZENE-1-SULFONATE 2-CHLORO-3-[(5-NITRO-2-PYRIDYL)OXY]PYRIDINE 2-CHLORO-5-FLUORO-3-HYDROXYPYRIDINE DI(2-CHLORO-3-PYRIDYL) 5-(TERT-BUTYL)ISOPHTHALATE 2,4-DICHLORO-3-METHOXYQUINOLINE 2-CHLORO-3-PYRIDYL 3,5-DICHLOROBENZENE-1-SULFONATE 2-CHLORO-3-HYDROXYPYRIDINE-4-CARBOXYLIC ACID ETHYL 4-[(2-CHLORO-3-PYRIDYL)OXY]-5,8-DIFLUOROQUINOLINE-3-CARBOXYLATE 2-[(2-CHLORO-3-PYRIDYL)OXY]-3-NITROPYRIDINE AURORA KA-6972
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