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| | 1-Ethynyl-1-cyclohexanol Basic information |
| | 1-Ethynyl-1-cyclohexanol Chemical Properties |
| Melting point | 30-33 °C(lit.) | | Boiling point | 180 °C(lit.) | | density | 0.967 g/mL at 25 °C(lit.) | | vapor pressure | <1 mm Hg ( 20 °C) | | refractive index | 1.481-1.484 | | Fp | 163 °F | | storage temp. | Store below +30°C. | | solubility | 10 g/L (20°C) | | pka | 13.34±0.20(Predicted) | | form | Liquid After Melting | | color | Clear colorless to light yellow | | PH | 7 (1g/l, H2O, 20℃) | | explosive limit | 1.3-8.7%(V) | | Water Solubility | 10 g/L (20 ºC) | | BRN | 471404 | | InChIKey | QYLFHLNFIHBCPR-UHFFFAOYSA-N | | LogP | 1.49 at 25℃ | | CAS DataBase Reference | 78-27-3(CAS DataBase Reference) | | NIST Chemistry Reference | Cyclohexanol, 1-ethynyl-(78-27-3) | | EPA Substance Registry System | Cyclohexanol, 1-ethynyl- (78-27-3) |
| Hazard Codes | Xn,Xi | | Risk Statements | 21/22-36-36/37/38-20/21/22-36/38 | | Safety Statements | 36/37-36/37/39-26-36-22 | | RIDADR | UN 2811 6.1/PG 3 | | WGK Germany | 1 | | RTECS | GV9100000 | | Autoignition Temperature | 365 °C | | TSCA | Yes | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29061900 | | Toxicity | LD50 orally in Rabbit: 583 mg/kg LD50 dermal Rabbit 973 mg/kg |
| | 1-Ethynyl-1-cyclohexanol Usage And Synthesis |
| Chemical Properties | Colorless liquid | | Uses | Stabilization of chlorinated organic compounds, intermediate, corrosion inhibitor for mineral acids, medicine (sedative). | | Uses | 1-Ethynyl-1-cyclohexanol (ECHO) can undergo acetylation in the presence of a catalytic amount of ruthenium chloride at room temperature. It can be used to synthesize novel organotellurium(IV) compounds with potent inhibitory activity towards Cathepsin B. The polymerization of ECHO by transition metal catalysts leads to the formation of poly(ECHO). It can also react with transition metal hydride complexes to form vinyl derivatives by inserting into the M-H bonds. | | Synthesis Reference(s) | Organic Syntheses, Coll. Vol. 3, p. 416, 1955
Synthetic Communications, 18, p. 131, 1988 DOI: 10.1080/00397918808077336 | | Flammability and Explosibility | Nonflammable |
| | 1-Ethynyl-1-cyclohexanol Preparation Products And Raw materials |
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