ChemicalBook Product Catalog Biochemical Engineering Inhibitors Neuronal Signaling Histamine Receptor Antagonists Roxatidine acetate hydrochloride

Roxatidine acetate hydrochloride

Roxatidine acetate hydrochloride Basic information
Product Name:Roxatidine acetate hydrochloride
Synonyms:ROXATIDINE HCL ACETATE;2-(acetyloxy)-n-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)-acetamidmonoh;2-acetoxy-n-(3-(m-(1-piperidinylmethyl)phenoxy)propyl)acetamidehydrochloride;2-hydroxy-n-(3-(m-(piperidinomethyl)phenoxy)propyl)-acetamidacetate(ester;2-hydroxy-n-(3-(m-(piperidinomethyl)phenoxy)propyl)acetamideacetate(ester);aceroxatidinehydrochloride;acetamide,2-hydroxy-n-(3-(m-(1-piperidinylmethyl)phenoxy)propyl)-,acetate,;tzu0460
CAS:93793-83-0
MF:C19H29ClN2O4
MW:384.89756
EINECS:685-494-1
Product Categories:Miscellaneous Biochemicals;MEFOXIN;Amines;Aromatics;Heterocycles;Other APIs;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API;93793-83-0
Mol File:93793-83-0.mol
Roxatidine acetate hydrochloride Structure
Roxatidine acetate hydrochloride Chemical Properties
Melting point 145-146°
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO: 78 mg/ml; Ethanol: 12 mg/ml; Water: 77 mg/ml
form powder to crystal
color White to Almost white
Merck 14,8274
Safety Information
RTECS AC3855000
HS Code 2933.39.9200
MSDS Information
Roxatidine acetate hydrochloride Usage And Synthesis
DescriptionRoxatidine acetate hydrochloride is an H2 antagonist, differing considerably in structure from other marketed agents(cimetidine, ranitidine and famotidine) in this category. It is useful in the treatment of gastric, duodenal and anastomotic ulcers, Zollinger-Ellison syndrome and peptic esophagitis.
DescriptionRoxatidine acetate is a competitive histamine H2 receptor antagonist that upon oral absorption is rapidly converted to its active metabolite roxatidine. By inhibiting the binding of histamine to H2 receptors, roxatidine reduces both intracellular cAMP concentrations and gastric acid secretion by parietal cells.
Chemical PropertiesWhite Solid
OriginatorTeikoku Hormone (Japan)
Usesantibacterial
UsesA histamine H2-receptor antagonist. It is used to inhibit gastric acid secretion; an antiulcer agent.
DefinitionChEBI: Roxatidine acetate hydrochloride is a member of piperidines. It contains a Roxane.
Brand nameALTAT
Roxatidine acetate hydrochloride Preparation Products And Raw materials
Trimethoxypropylsilane Sodium acetate Topotecan hydrochloride ISOPROPYLHYDRAZINE HYDROCHLORIDE Cellulose acetate Roxatidine acetate Butyl acetate ACETATE Ethyl acetate Thioacetamide Vinyl acetate 3-Chloropropyltriethoxysilane Benzyl acetate 3-Aminopropyltriethoxysilane N,N-Dimethylacetamide 3-Chloropropyltrimethoxysilane 3-Mercaptopropyltriethoxysilane 2-Butoxyethyl acetate
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