DL-Histidine

DL-Histidine Basic information
Product Name:DL-Histidine
Synonyms:1H-Imidazole-4-alanine;D-Histidine/L-histidine,(1:1);rac-(R*)-2-Amino-3-(4-imidazolyl)propionic acid;DL-Histidine,98%;DL-Histdine;H-DL-His-OH (DL-Histidine;DL-Histidine 0;DL-Histidine 
CAS:4998-57-6
MF:C6H9N3O2
MW:155.15
EINECS:225-660-9
Product Categories:alpha-Amino Acids;Amino Acids;Biochemistry;Amino Acids
Mol File:4998-57-6.mol
DL-Histidine Structure
DL-Histidine Chemical Properties
Melting point 273 °C (dec.)(lit.)
Boiling point 278.95°C (rough estimate)
density 1.3092 (rough estimate)
refractive index 1.6500 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility 0.5 M HCl: soluble
pka1.8(at 25℃)
form powder to crystal
color White to Almost white
Merck 14,4720
BRN 7800
CAS DataBase Reference4998-57-6(CAS DataBase Reference)
EPA Substance Registry SystemHistidine (4998-57-6)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 22-24/25-36/37-26
WGK Germany 3
HS Code 29339900
MSDS Information
ProviderLanguage
DL-2-Amino-3-(1H-imidazol-4-yl)propanoic acid English
ACROS English
SigmaAldrich English
DL-Histidine Usage And Synthesis
Chemical Propertieswhite to slightly yellow crystalline powder
Useshistidine is a skin-conditioning amino acid.
UsesDL-Histidine has been used to study the fouling behaviour of polyethersulfone ultrafiltration membranes made with different PVP (polyvinylpyrrolidone).
DefinitionChEBI: An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3.
Synthesis Reference(s)Journal of the American Chemical Society, 67, p. 502, 1945 DOI: 10.1021/ja01219a513
Chemical and Pharmaceutical Bulletin, 35, p. 3447, 1987
Biochem/physiol ActionsL-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.
DL-Histidine Preparation Products And Raw materials
Raw materialsErythromycin Estolate-->Histamine
Preparation ProductsALLYLUREA
Methyl L-histidinate dihydrochloride Acetaminophen BOC-D-HIS-OH DL-Histidine N-CBZ-DL-HISTIDINE Glucosamine EC 2.6.1.2 6-Aminocaproic acid L-ANSERINE NITRATE Imidazole N-ALPHA-BENZOYL-L-HISTIDINE 1-METHYL-L-HISTIDINE N-Acetyl-L-histidine Tris(hydroxymethyl)aminomethane N-PHTHALOYL-DL-HISTIDINE AMINO ACIDS DL-HISTIDINE DIHYDROCHLORIDE,DL-HISTIDINE DIHYDROCHLORIDE H-ALA-HIS-OH

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