4,6-Dichloro-2-methylpyrimidine

4,6-Dichloro-2-methylpyrimidine Basic information
Product Name:4,6-Dichloro-2-methylpyrimidine
Synonyms:BUTTPARK 52\14-70;2-MDCP;2-METHYL-4,6-DICHLOROPYRIMIDINE;4,6-DICHLORO-2-METHYLPYRIMIDINE;4,6-Dichloro-2-methylpyrimidiine;Pyrimidine, 4,6-dichloro-2-methyl-;4,6-Dichloro-2-methylpyrimidine ,99%;4,6-Dichloro-2-Methylpyrimidine/2,4-dichloro-6-methylpyrimidine
CAS:1780-26-3
MF:C5H4Cl2N2
MW:163
EINECS:605-815-0
Product Categories:Heterocycle-Pyrimidine series;alkyl chloride;APIs & Intermediate;Pyrimidine;Halides;Pyrimidines;Pyrazines, Pyrimidines & Pyridazines;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;PyrimidinesHeterocyclic Building Blocks;bc0001
Mol File:1780-26-3.mol
4,6-Dichloro-2-methylpyrimidine Structure
4,6-Dichloro-2-methylpyrimidine Chemical Properties
Melting point 41.5-45.5 °C (lit.)
Boiling point 210.8±20.0 °C(Predicted)
density 1.404±0.06 g/cm3(Predicted)
Fp 208 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
pka-3.84±0.30(Predicted)
form Crystalline Powder or Crystals
color White to off-white
InChIKeyFIMUTBLUWQGTIJ-UHFFFAOYSA-N
CAS DataBase Reference1780-26-3(CAS DataBase Reference)
Safety Information
Hazard Codes C,N,Xn
Risk Statements 34-51/53-43-22
Safety Statements 26-36/37/39-45-61-36/37
RIDADR UN 3261 8/PG 2
WGK Germany 3
HazardClass 8
PackingGroup III
HS Code 29335990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
4,6-Dichloro-2-methylpyrimidine Usage And Synthesis
Chemical PropertiesWhite to off-white solid
Uses4,6-Dichloro-2-methylpyrimidine, is a versatile building block used for the synthesis of more complex pharmaceutical and biologically active compounds, such as Dasatinib (D290002), and its derivatives.
4,6-Dichloro-2-methylpyrimidine Preparation Products And Raw materials
Preparation ProductsMoxonidine-->Dasatinib monohydrate-->4-CHLORO-2,6-DIMETHYLPYRIMIDINE-->4-Pyrimidinamine, 2-methyl- (9CI)-->4-Amino-6-chloro-2-methylpyrimidine-->Pyrimidine, 4-amino-2-methyl-6-(methylamino)- (6CI,8CI)-->4,6-bis(3,5-dichlorophenyl)-2-methylpyrimidine-->6-chloro-N,N,2-trimethyl-4-pyrimidinamine-->4-(6-CHLORO-2-METHYLPYRIMIDIN-4-YL)MORPHOLINE-->6-chloro-N-ethyl-2-MethylpyriMidin-4-aMine-->2-(4-(6-chloro-2-methylpyrimidin-4-yl)piperazin-1-yl)ethanol-->N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide-->4-chloro-6-(4-fluorophenyl)-2-methylpyrimidine-->Dasatinib
4,6-DICHLORO-5-NITRO-2-(TRIFLUOROMETHYL)PYRIMIDINE 4,6-DICHLORO-5-[4-(HEXYLOXY)PHENYL]-2-(4-PENTYLPHENYL)PYRIMIDINE 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine 2-Methylpyrimidine 4,6-Dichloro-2-methylpyrimidine 2-Chloro-5-chloromethylpyridine Dichloromethylsilane 2-tert-butyl-4,6-dichloro-5-methylpyrimidine 4,6-Dihydroxypyrimidine 4,6-Dichloro-2-methyl-5-nitropyrimidine Dichloromethylphenylsilane Dichloroacetic acid Fenclorim 4,6-Dichloropyrimidine 5-ALLYL-4,6-DICHLORO-2-METHYLPYRIMIDINE Pirimiphos-methyl 4-Ethyl-5-fluoro-6-hydroxypyrimidine Dichlorodimethylsilane

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