ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Amino alcohol derivative (R)-(-)-2-Amino-3-methyl-1-butanol

(R)-(-)-2-Amino-3-methyl-1-butanol

(R)-(-)-2-Amino-3-methyl-1-butanol Basic information
Product Name:(R)-(-)-2-Amino-3-methyl-1-butanol
Synonyms:2-AMINO-3-METHYLBUTAN-1-OL;(R)-(-)-2-Amino-3-methyl-1-butanol 98%;D-Valinol≥ 99% (GC);D-Valinol,99%e.e.;(R)-(-)-2-AMINO-3-METHYLBUTANOL FOR SYNT;（R）-2-Amino-3-mehylbutanol;(R)-()-2-Amino-3-methyl-1-butanol,D-Valinol;(R)-(-)-2-Amino-3-me
CAS:4276-09-9
MF:C5H13NO
MW:103.16
EINECS:217-975-5
Product Categories:Amino Alcohols (Chiral);Asymmetric Synthesis;Chiral Building Blocks;Synthetic Organic Chemistry;Chiral Compound;Amino alcohols;Pharmaceutical Intermediates;Pharmaceutical Raw Materials;chiral;Valine [Val, V];Amino Alcohols;bc0001
Mol File:4276-09-9.mol
(R)-(-)-2-Amino-3-methyl-1-butanol Structure
(R)-(-)-2-Amino-3-methyl-1-butanol Chemical Properties
Melting point 35-36 °C(lit.)
alpha -16.5 º (c=10, EtOH)
Boiling point 189-190 °C(lit.)
density 0.931 g/mL at 20 °C(lit.)
refractive index n20/D 1.455
Fp 194 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka12.82±0.10(Predicted)
form Low Melting Crystals or Crystalline Mass
color White to light yellow
optical activity[α]20/D 16°, c = 10 in ethanol
Sensitive Air Sensitive
BRN 1719138
InChIKeyNWYYWIJOWOLJNR-YFKPBYRVSA-N
CAS DataBase Reference4276-09-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37-36-36/37/38
WGK Germany 3
F 10-34
HS Code 29051990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
(R)-(-)-2-Amino-3-methyl-1-butanol Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powde
UsesD-Valinol is used as a reagent in the synthesis of the HIV type 1 integrase inhibitor Elvitegravir (E509000). D-Valinol is also used in the preparation of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally active GSK-3β inhibitors for Alzheimer''s disease.
(R)-(-)-2-Amino-3-methyl-1-butanol Preparation Products And Raw materials
Preparation Products(R)-(+)-4-Isopropyl-2-oxazolidinone-->Carbamic acid, [(1S)-1,2-dimethylpropyl]-, 1,1-dimethylethyl ester (9CI)
Methylparaben Methyl 6-Aminopenicillanic acid (R)-(-)-2-Amino-3-methyl-1-butanol Lithium bis(trimethylsilyl)amide Ampicillin Bensulfuron methyl D-tert-Butylglycine EC 2.6.1.2 D-PENICILLAMINE DISULFIDE Penicillin G potassium salt AC-D-VAL-OH Kresoxim-methyl (S)-(+)-2-Amino-1-butanol Tris(hydroxymethyl)aminomethane Methyl acrylate TRISTEARIN Methyl bromide
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