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| | DL-Homocysteine Basic information |
| Product Name: | DL-Homocysteine | | Synonyms: | HOMOCYSTEINE, DL-(P);DL-Homocysteine,2-Amino-4-mercaptobutyric acid;DL-HoMocystein;(+-)-homocysteine;dl-2-amino-4-mercaptobutyricacid;usafb-12;2-AMINO-4-MERCAPTOBUTYRIC ACID;2-AMINO-4-MERCAPTOBUYRIC ACID | | CAS: | 454-29-5 | | MF: | C4H9NO2S | | MW: | 135.18 | | EINECS: | 207-222-9 | | Product Categories: | Amino Acids;Amino Acids | | Mol File: | 454-29-5.mol |  |
| | DL-Homocysteine Chemical Properties |
| Melting point | 232-233 °C(lit.) | | Boiling point | 299.7±35.0 °C(Predicted) | | density | 1.149 (estimate) | | refractive index | 1.5480 (estimate) | | Fp | >230 °F | | storage temp. | -20°C | | solubility | H2O: soluble | | pka | 2.22, 8.87, 10.86(at 25℃) | | form | solid | | color | White to Off-White | | optical activity | [α]/D 0±1°, c = 1 in H2O | | Merck | 14,4734 | | BRN | 1721683 | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. | | InChIKey | FFFHZYDWPBMWHY-UHFFFAOYSA-N | | LogP | 0.220 (est) | | CAS DataBase Reference | 454-29-5(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | MT0175000 | | F | 10-23 | | HS Code | 29309090 | | Toxicity | LD50 intraperitoneal in mouse: 500mg/kg |
| | DL-Homocysteine Usage And Synthesis |
| Chemical Properties | white powder | | Uses | DL-Homocysteine has been used to induce hyperhomocysteinemia in Sprague–Dawley rats. It has also been used to study the effects of hyperhomocysteinemia on atherosclerosis in apolipoprotein E-deficient mice. | | Definition | ChEBI: A sulfur-containing amino acid consisting of a glycine core with a 2-mercaptoethyl side-chain. | | Biochem/physiol Actions | Homocysteine is a sulfhydryl-containing amino acid, synthesized from methionine. It is a non-essential, non-proteinogenic amino acid. It is an important determinant of the methylation cycle and is present in the plasma in four forms. An abnormally high level of homocysteine leads to hyperhomocysteinemia and also promotes atherosclerosis. | | Purification Methods | Purify it as for the L-isomer. [Allen & Steinmann J Am Chem Soc 74 3932 1952, and references for the L-isomer above, Beilstein 4 IV 3189.] |
| | DL-Homocysteine Preparation Products And Raw materials |
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