ChemicalBook Product Catalog Pharmaceutical intermediates Bulk Drug Intermediates (S)-(+)-3-Hydroxytetrahydrofuran

(S)-(+)-3-Hydroxytetrahydrofuran

(S)-(+)-3-Hydroxytetrahydrofuran Basic information
Product Name:(S)-(+)-3-Hydroxytetrahydrofuran
Synonyms:(S)-TETRAHYDROFURAN-3-OL;(S)-(+)-TETRAHYDRO-3-FURANOL;(S)-(+)-3-HYDROXY TETAHYDRO FURAN;(S)-(-)-3-HYDROXY TETRAHYDRO FURAN;(3S)-oxolan-3-ol;(2S)-1,4-Epoxy-2-hydroxybutane, (3S)-Tetrahydrofuran-3-ol, (3S)-Oxolan-3-ol;Afatinib intermediate B;(S)-(+)-3-Hydroxytetrahydrofuran, ee: 95%
CAS:86087-23-2
MF:C4H8O2
MW:88.11
EINECS:425-090-2
Product Categories:Afatinib intermediate;Chiral Building Blocks;Chiral Reagents;Furans;Simple Alcohols (Chiral);Synthetic Organic Chemistry;Alcohols, Hydroxy Esters and Derivatives;Chiral Compounds;Starting Raw Materials & Intermediates;Small molecule;Tetrahydrofuran Series;bc0001;86087-23-2
Mol File:86087-23-2.mol
(S)-(+)-3-Hydroxytetrahydrofuran Structure
(S)-(+)-3-Hydroxytetrahydrofuran Chemical Properties
alpha 18.5 º (c=2 MeOH)
Boiling point 80 °C/15 mmHg (lit.)
density 1.103 g/mL at 25 °C (lit.)
vapor pressure 47Pa at 25℃
refractive index n20/D 1.45(lit.)
Fp 175 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform, Methanol (Slightly)
form Liquid
pka14.49±0.20(Predicted)
Specific Gravity1.11
color Clear colorless to pale yellow
optical activity[α]20/D +17.5°, c = 2.4 in methanol
Water Solubility soluble
BRN 4652609
Stability:Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKeyXDPCNPCKDGQBAN-BYPYZUCNSA-N
LogP-0.784 at 22℃ and pH6.8
Surface tension72mN/m at 1g/L and 25℃
CAS DataBase Reference86087-23-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
RIDADR NA 1993 / PGIII
WGK Germany 3
HS Code 29321900
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
(S)-(+)-3-Hydroxytetrahydrofuran Usage And Synthesis
Chemical PropertiesColourless Liquid
UsesAmprenavir and Fosamprenavir intermediate
Uses(S)-(+)-3-Hydroxytetrahydrofuran is a useful reagent for the preparation of pyrazolo triazin ylamine derivatives as adenosine receptor antagonists.
(RS)-3-Hydroxytetrahydrofuran 3,5-HYDROXY TETRAHYDROFURAN Tetrahydro (S)-(+)-3-Hydroxytetrahydrofuran 1-((3R,4S,5R)-5-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-4-HYDROXYTETRAHYDROFURAN-3-YL)-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE 1-((3S,4R,5S)-5-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-4-HYDROXYTETRAHYDROFURAN-3-YL)-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE POLY(TETRAHYDROFURAN) STANDARD 20000 POLY(TETRAHYDROFURAN) STANDARD 15000 2-Methyl-3-hydroxytetrahydrofuran 1-O-[(3S,4R)-3-HYDROXYTETRAHYDROFURAN-4-YL]-ALPHA-D-GLUCOPYRANOSIDE 3,4,3'-TRISPHOSPHATE, 4TEA 5-(3-PYRIDYL)-2-HYDROXYTETRAHYDROFURAN 3-HYDROXYTETRAHYDROFURAN 99%,3-HYDROXYTETRAHYDROFURAN (S)-(+)-3-HYDROXYTETRAHYDROFURAN-D4 Tetrahydrofuran 3-(carboxymethyl)-5-(6-(2,4-dichlorophenyl)hexyl)-3-hydroxytetrahydrofuran-2-one 2-Methyltetrahydrofuran 3-(S)-HYDROXY TETRAHYDROFURAN 1-[(4α-Hydroxytetrahydrofuran)-2β-yl]-5-fluorouracil
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