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| | stephanine Basic information |
| Product Name: | stephanine | | Synonyms: | 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-9-methoxy-7-methyl-, (7aR)-;(7aR)-9-Methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline | | CAS: | 517-63-5 | | MF: | C19H19NO3 | | MW: | 309.36 | | EINECS: | | | Product Categories: | Miscellaneous Natural Products | | Mol File: | 517-63-5.mol |  |
| | stephanine Chemical Properties |
| Melting point | 155 °C | | Boiling point | 463.6±45.0 °C(Predicted) | | density | 1.268±0.06 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Cryst. | | pka | 7.03±0.20(Predicted) |
| | stephanine Usage And Synthesis |
| Description | l-Stephanine is a potent and highly selective alpha 1 adrenoceptor blocker, inhibits anococcygeus muscle contraction induced by phenylephrine with pA2 values of 6.76.
Stephanine and crebanine have high inhibitory activity against gram-positive animal pathogenic bacteria, with MIC values of 0.078-0.312g/l, but low inhibitory activity against gram-negative animal pathogenic bacteria, they also inhibit hyphal growth of the plant pathogens Cercospora kaki.
3. Stephanine, pseudopalmatine , tetrahydropalmatine , and xylopinine show significant antiplasmodial activities with IC(50) ranged from 2 uM to 53 uM. | | target | Adrenergic Receptor | Antifection |
| | stephanine Preparation Products And Raw materials |
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