CHICAGO SKY BLUE 6B

CHICAGO SKY BLUE 6B Basic information
Product Name:CHICAGO SKY BLUE 6B
Synonyms:chicago sky blue 6B (C.I. 24410);Chicago Sky Blue?B;PontamineSkyBlueBX;tetrasodium 6,6'-[(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-amino-5-hydroxynaphthalene-1,3-disulphonate];Direct Lake Blue 6B;1,3-Naphthalenedisulfonic acid, 6,6-(3,3-dimethoxy1,1-biphenyl-4,4-diyl)bis(azo)bis4-amino-5-hydroxy-, tetrasodium salt;1,3-naphthalenedisulfonicacid,6,6’-[(3,3’-dimethoxy[1,1’-biphenyl]-4,4’-diyl);6,8-naphthalenedisulfonicacid,3,3’-((3,3’-dimethoxy-4,4’-biphenylene)bis(azo)
CAS:2610-05-1
MF:C34H29N6NaO16S4
MW:928.86
EINECS:220-026-8
Product Categories:Organics;Inhibitors;Dyes and Pigments
Mol File:2610-05-1.mol
CHICAGO SKY BLUE 6B Structure
CHICAGO SKY BLUE 6B Chemical Properties
storage temp. room temp
solubility DMSO (Very Slightly, Sonicated, Heated), Methanol (Very Slightly, Heated), Water
form powder
Colour Index 24410
color Dark Blue to Very Dark Blue
Water Solubility Soluble in water (1 mg/ml).
Stability:Stable. Probably combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference2610-05-1
EPA Substance Registry SystemC.I. Direct Blue 1, tetrasodium salt (2610-05-1)
Safety Information
Hazard Codes Xn,T
Risk Statements 20/21/22-45
Safety Statements 22-36-45-53
RIDADR 3143
WGK Germany 3
RTECS QJ6430000
TSCA Yes
Hazardous Substances Data2610-05-1(Hazardous Substances Data)
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
CHICAGO SKY BLUE 6B Usage And Synthesis
Chemical Propertiesgreenish blue powder
UsesCompetitive glutamate uptake inhibitor
UsesChicago Sky Blue 6B is a counterstain for background autofluorescence in fluorescence and immunofluorescence histochemistry. It helps in the examination of blood plasma permeation.
UsesChicago Sky Blue 6B is a counterstain for background autofluorescence in fluorescence and immunofluorescence histochemistry. It has also been used as a filling in glass pipette electrodes for electrophysiological recordings in the brain sections of rats.
Preparation3,3′-Dimethoxylbenzidine double nitriding, in alkaline conditions and 4-Amino-5-hydroxynaphthalene-1,3-disulfonic acid (2 Moore) coupled.
General DescriptionBright greenish-blue solid or dark blue powder.
Air & Water ReactionsAzo dyes can be explosive when suspended in air at specific concentrations. Slightly soluble in water.
Reactivity ProfileCHICAGO SKY BLUE 6B is an azo compound. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides. Cleavage of the diazo group by reducing agents may lead to benzidine production.
Fire HazardFlash point data for CHICAGO SKY BLUE 6B are not available; however, CHICAGO SKY BLUE 6B is probably combustible.
Biological ActivityPotent inhibitor of L-glutamate uptake into synaptic vesicles.
Biochem/physiol ActionsChicago Sky Blue 6B is a large organic acid, structurally related to glutamate, that is a potent and efficient competitive inhibitor of vesicular glutamate uptake.
Safety ProfileAn experimental teratogen. Other experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx Na2O, and SOx
storageStore at RT
Properties and Applicationscolourful green light blue. Blue powder. Soluble in water solution for bright blue, solubility of 50 g/L (80 ℃), slightly soluble in soluble fiber element, insoluble in other organic solvents. The strong sulfuric acid solution for blue-ray green, blue for diluted; In nitric acid solution for red light purple. The dye solution to join 10% no change sulfuric acid; Add thick sodium hydroxide solution for red light blue. Cellulose fiber of dyeing, the dye well after sex is very good, in 60 ~ 80 ℃ when supreme affinity, discharge sex is very good. In dyeing of copper (colored light turned green, a slight change in iron ion. Mainly used for cotton, viscose and other cellulose fibers, silk, nylon, rayon/nylon blend fabric, paper and biological stain can also be used for cotton and viscose fabric is mainly used for direct printing of cotton, rayon and other cellulose fiber, silk, nylon, rayon / nylon blend fabric, paper and biological stain can also be used for cotton and viscose fabric direct printing.
Standard Acid Resistance Alkali Resistance Light Fastness Soaping Water
Fading Stain Fading Stain
ISO 5 4 1 2 2
AATCC 5 1 1 3-4 1
Purification MethodsFree it from other electrolytes by adding aqueous sodium acetate to a boiling solution of the dye in distilled water. After standing, the salted-out dye is filtered on a Büchner funnel, the process being repeated several times. Finally, the precipitated dye is boiled several times with absolute EtOH to wash out any sodium acetate, then dried (as the sodium salt) at 105o. [McGregor et al. Trans Faraday Soc 58 1045 1962, Beilstein 16 II 259.]
CHICAGO SKY BLUE 6B Preparation Products And Raw materials
Raw materialso-Dianisidine-->o-Dianisidine-->4-amino-5-hydroxynaphthalene-1,3-disulphonic acid
Sodium 4-amino-1-naphthalenesulfonate 7-AMINO-2-NAPHTHALENESULFONIC ACID SODIUM SALT CHICAGO SKY BLUE 6B 1-AMINO-8-NAPHTHOL-4-SULFONIC ACID benzene-1,3-disulphonic acid 3-METHOXYBIPHENYL 4-Amino-1,3-benzenedisulfonic acid Benzidine Sodium 5-hydroxynaphthalene-1-sulphonate Naphthionic acid 3'-METHOXY-BIPHENYL-4-YLAMINE HYDROCHLORIDE 3-METHOXYBENZIDINE 6-Amino-m-cresol 4-AMINO-1-NAPHTHALENESULFONIC ACID SODIUM SALT 6-AMINO-1,3-NAPHTHALENEDISULFONIC ACID DISODIUM SALT 2,2'-DIHYDROXYAZOBENZENE 2-Chloro-5-hydroxypyridine 1,3-BENZENEDISULFONIC ACID DISODIUM SALT

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