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| | gracillin Basic information |
| | gracillin Chemical Properties |
| Melting point | 290-293℃ (DEC.) | | density | 1.42 | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Soluble in DMSO, methanol and pyridine | | form | powder | | pka | 12.78±0.70(Predicted) | | color | White |
| | gracillin Usage And Synthesis |
| Description | Gracillin is a steroidal saponin that has been found in C. speciosus and has diverse biological activities. It reduces cell growth in a panel of 58 leukemia, non-small cell lung, colon, CNS, prostate, melanoma, ovarian, renal, and breast cancer cell lines (GI50s = 0.58-2.44 μM). Gracillin reduces growth of fish Ich parasite (I. multifiliis) theronts (EC50 = 0.53 mg/L) and induces 100 and 92.5% mortality of I. multifiliis protomonts and encysted tomonts, respectively, when used at a concentration of 0.8 mg/L. It decreases the number of I. multifiliis-infected goldfish by approximately 75% when used at a concentration of 1 mg/L in tank water. Gracillin (100 mg/kg) reduces ear edema induced by arachidonic acid in mice. | | Uses | Gracillin is a steroidal glycoside from the rhizomes of the family Dioscoreaceae with potential anti-proliferative effects. | | Definition | ChEBI: Gracillin is a triterpenoid. |
| | gracillin Preparation Products And Raw materials |
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