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| | Vanillylidenacetone Basic information |
| | Vanillylidenacetone Chemical Properties |
| Melting point | 125-130 °C | | Boiling point | 268.19°C (rough estimate) | | density | 1.1503 (rough estimate) | | FEMA | 3738 | VANILLYLIDENE ACETONE | | refractive index | 1.4600 (estimate) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml). | | pka | 9.94±0.31(Predicted) | | form | solid | | color | Pale yellow | | Odor | at 100.00 %. sweet powdery vanilla creamy balsam | | Odor Type | vanilla | | JECFA Number | 732 | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. | | LogP | 1.40 | | CAS DataBase Reference | 1080-12-2(CAS DataBase Reference) | | EPA Substance Registry System | 3-Buten-2-one, 4-(4-hydroxy-3-methoxyphenyl)- (1080-12-2) |
| Risk Statements | 36/37/38 | | Safety Statements | 26-36/37/39 | | WGK Germany | 3 | | RTECS | EM9960000 | | F | 10-23 | | HS Code | 29145090 | | Toxicity | LD50 intraperitoneal in mouse: 610mg/kg |
| | Vanillylidenacetone Usage And Synthesis |
| Description | Dehydrozingerone (1080-12-2) is a structural half analog of curcumin (Cat.# 10-1243) and is isolated from ginger rhizomes. Dehydrozingerone displays antioxidant, antibacterial and antifungal properties.1 It has also been shown to possess various antitumor effects2,3 and inhibit growth factor/peroxide-stimulated vascular smooth muscle function4. | | Chemical Properties | Vanillylidene acetone has a very sweet, warm and tenacious odor. | | Uses | Vanillylidenacetone is one of ferulic acid derivatives. Studies have shown that vanillyl acetone has a certain inhibitory effect on Amaranthus, barnyardgrass, matang, dogwood and rape, among which the best inhibitory effect is on rape and Amaranthus. | | Definition | ChEBI: Dehydrozingerone is a hydroxycinnamic acid. | | Taste threshold values | Taste characteristics at 200 ppm: balsamic vanilla, with sweet aromatic spicy nuances. | | References | 1) Kubra et al. (2014), Structure-function activity of dehydrozingerone and its derivatives as antioxidant and antimicrobial compounds; J. Food Sci. Technol., 51 245
2) Motohashi et al. (1998), Inhibitory effects of dehydrozingerone and related compounds on 12-O-tetradecanoylphorbol-13-acetate induced Epstein-Barr virus early antigen activation; Cancer Lett., 134 37
3) Yogosawa et al. (2012), Dehydrozingerone, a structural analog of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells; J. Nat. Prod., 75 2088
4) Liu et al. (2008), Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function; J. Cardiovasc. Pharmacol., 52 422 |
| | Vanillylidenacetone Preparation Products And Raw materials |
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