4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt

4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt Basic information
Product Name:4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt
Synonyms:[(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl sulfate;4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt;4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt;4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate Sodium Salt;4-Methyl-7-[(6-O-sulfo-β-D-galactopyranosyl)oxy]-;4-Methyl-7-[(6-O-sulfo-beta-D-galactopyranosyl)oxy]-2H-1-benzopyran-2-one monosodium salt;[(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-2-yl]methoxysulfonyloxysodium;4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt
CAS:206443-06-3
MF:C16H17NaO11S
MW:440.35435
EINECS:1533716-785-6
Product Categories:Carbohydrates & Derivatives;Fluorescent Labels & Indicators
Mol File:206443-06-3.mol
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt Structure
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt Chemical Properties
Melting point 196-198?C
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility Methanol (Slightly, Sonicated), Water (Slightly)
form Solid
color White to Off-White
Stability:-20?C Freezer, Under Inert Atmosphere
Safety Information
HS Code 2932209090
MSDS Information
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt Usage And Synthesis
Description4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.
Chemical PropertiesWhite Solid
UsesUsed for the determination of galactose-6-sulphate sulphatase activity. Used in the diagnosis of Mucopolysaccharidosis IV A.
Uses4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt is used for the determination of galactose-6-sulphate sulphatase activity,it is used in the diagnosis of Mucopolysaccharidosis IV A.
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt Preparation Products And Raw materials

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