CERIVASTATIN SODIUM

CERIVASTATIN SODIUM Basic information
Product Name:CERIVASTATIN SODIUM
Synonyms:RIVASTATIN;sodium 7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-dipropan-2-yl-pyrid in-3-yl]-3,5-dihydroxy-hept-6-enoate;LIPOBAY;BAYCOL;CERIVASTATIN NA;CERIVASTATIN, SODIUM SALT;7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-dipropan-2-yl-pyrid in-3-yl]-3,5-dihydroxy-hept-6-enoate;(3R,5S,6E)-7-[4-(p-Fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl]-3,5-dihydroxy-6-heptenoic acid
CAS:145599-86-6
MF:C26H34FNO5
MW:459.55
EINECS:
Product Categories:Active Pharmaceutical Ingredients
Mol File:145599-86-6.mol
CERIVASTATIN SODIUM Structure
CERIVASTATIN SODIUM Chemical Properties
Melting point >176oC (dec.)
Boiling point 646.3±55.0 °C(Predicted)
density 1.181±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility Ethanol (Slightly), Methanol (Slightly), Water (Slightly)
pkapKa 4.38 (H2O t=25 I=0.025) (Uncertain);5.29(H2O t=25 I=0.025) (Uncertain)
form Solid
color White to Off-White
Stability:Hygroscopic
CAS DataBase Reference145599-86-6(CAS DataBase Reference)
EPA Substance Registry System6-Heptenoic acid, 7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1- methylethyl)-3-pyridinyl]-3,5-dihydroxy-, (3R,5S,6E)- (145599-86-6)
Safety Information
Hazardous Substances Data145599-86-6(Hazardous Substances Data)
MSDS Information
CERIVASTATIN SODIUM Usage And Synthesis
Usesassimilate cholesterol
DefinitionChEBI: (3R,5S)-3,5-dihydroxyhept-6-enoic acid in which the (7E)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cho esterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity.
Brand nameBaycol (Bayer);Cholstat.
CERIVASTATIN SODIUM Preparation Products And Raw materials
Azathioprine Pitavastatin Nifedipine Rofecoxib Cisapride Fluorine CERIVASTATIN SODIUM Sodium 3-HEPTENOIC ACID Cerivastatin sodium Oxygen 3-METHYL-5-VINYLPYRIDINE

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