Dihydralazine sulphate

Dihydralazine sulphate Basic information
Product Name:Dihydralazine sulphate
Synonyms:DIHYDRALAZINE SULFATE;DIHYDRALAZINE SULFATE HYDRATE;DIHYDRALAZINE SULPHATE;1,4-dihydrazinophthalazinesulfate;1,4-dihydrazino-phthalazinsulfate(1:1);depressan;1,4-Dihydrazinophthalazine hydrogen sulfate;HYDRATED DIHYDRALAZINE SULPHATE BP - BULK DRUG
CAS:7327-87-9
MF:C8H12N6O4S
MW:288.28
EINECS:230-808-0
Product Categories:Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:7327-87-9.mol
Dihydralazine sulphate Structure
Dihydralazine sulphate Chemical Properties
Melting point >235°C (subl.)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO: soluble1mg/mL
form powder
color Off-White to Pale Yellow
CAS DataBase Reference7327-87-9(CAS DataBase Reference)
Safety Information
WGK Germany 3
MSDS Information
Dihydralazine sulphate Usage And Synthesis
DescriptionDihydralazine sulfate is a vasodilator and an antihypertensive agent. It relaxes arterial smooth muscle by inhibiting the accumulation of intracellular free calcium. By relaxing vascular smooth muscle, vasodilators act to decrease peripheral resistance.
Chemical PropertiesOff-White Solid
UsesDihydralazine sulphate is an antihypertensive agent of the hydrazine class used during pregnancies in dialysis patients with familial mediterranean fever and cystinosis under hemodialysis.
ApplicationDihydralazine sulphate (Nepresol) is a dihydralazine-1,4-phthalazine derivative and used as an antihypertensive drug with actions and uses similar to those of hydralazine.
Mode of actioncell membrane | interferes
Dihydralazine sulphate Preparation Products And Raw materials
Tazobactam Impurity B Sumatriptan EP Impurity H 4-Hydrazinyl-1-phthalazinaMine Penehyclidine Impurity 18 3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide [3-[2-(diMethylaMino)ethyl]-2-[[3-[2-(diMethylaMino)ethyl]-1H-indol-5-yl]Methyl]-1H-indol-5-yl]-N-MethylMethanesulfonaMide, succinate salt Benzeneacetaldehyde, α-cyclopentyl- N-DesMethyl SuMatriptan Penehyclidine IMpurity SuMatriptan N-Oxide Neomycin sulfate Ophthazin Dihydralazine sulphate DIHYDRALAZINE SULPHATE (HYDRATED) - REFERENCE SPECTRUM SODIUM SULFATE Dinonylnaphthalenesulfonic acid Atropine sulfate Colistin sulfate

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