YUNACONITINE

YUNACONITINE Basic information
Product Name:YUNACONITINE
Synonyms:11aH-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine;Yunnaconitine;Yunaconitine GuayewuanineB;Aconitane-3,8,13,14-tetrol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-(4-methoxybenzoate), (1α,3α,6α,14α,16β)-;YUNACONITINE USP/EP/BP;Aconitane-3,8,13,14-tetrol,20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate14-(4-methoxybenzoate), (1a,3a,6a,14a,16b)-;(3R,4R,6S,6aS,7R,7aR,8R,9S,10S,11aR,12R,12aR,13R,14S)-11a-acetoxy-1-ethyl-4,9-dihydroxy-6,10,13-trimethoxy-3-(methoxymethyl)tetradecahydro-1H-3,6a,12-(epiethane[1,1,2]triyl)-7,9-methanonaphtho[2,3-b]azocin-8-yl 4-methoxybenzoate;(1alpha,3alpha,6alpha,14alpha,16beta)-8-(acetyloxy)-20-ethyl...
CAS:70578-24-4
MF:C35H49NO11
MW:659.77
EINECS:
Product Categories:Miscellaneous Natural Products;Alkaloids;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:70578-24-4.mol
YUNACONITINE Structure
YUNACONITINE Chemical Properties
Melting point 142-144℃
Boiling point 722.8±60.0 °C(Predicted)
density 1.34
solubility DMF: 1 mg/ml; DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml
form A solid
pka12.67±0.70(Predicted)
Stability:Hygroscopic
Safety Information
MSDS Information
YUNACONITINE Usage And Synthesis
UsesYunnaconitine is a metabolite of Aconitine (A189875), a neurotoxin that binds, activates tetrodotoxin-sensitive Na+ channels and prolongs the opening of the sodium-ion channel by suppressing conformat ional changes. Yunnaconitine is a deiterpene alkaloid, known to exhibit cytotoxic activity in human leukemic cell.
YUNACONITINE Preparation Products And Raw materials
Preparation ProductsACOFORESTININE
Acetylaconitine yunnanxane Theaflavin 3,3′-digallate 8-O-acetyl shanzhiside methyl ester 6-Gingerol 6-Shogaol Bullatine B Yuheiside 1-Methyl-L-tryptophan Yunnandaphninine G SodiuM DeMethylcantharidate Yunaconitoline 2-Ethylhexyl 4-hydroxybenzoate Dodecyl 4-hydroxybenzoate YUNACONITINE CIS-1,3-DIACETOXYCYCLOHEXANE 4-Benzoyloxycyclohexanol ISO-METHYL TETRAHYDROIONYL ACETATE

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