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| | methyl (3beta,19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate Basic information |
| Product Name: | methyl (3beta,19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate | | Synonyms: | Reserpiline;(3β,20α)-16,17-Didehydro-10,11-dimethoxy-19α-methyl-18-oxayohimban-16-carboxylic acid methyl ester;(3β,20α)-16,17-Didehydro-19α-methyl-10,11-dimethoxy-18-oxayohimban-16-carboxylic acid methyl ester;Einecs 205-005-3;Elliptamine;Methyl 16,17-didehydro-10,11-dimethoxy-19alpha-methyl-18-oxa-3beta,20alpha-yohimban-16-carboxylat;Oxayohimban-16-carboxylic acid, 16,17-didehydro-10,11-dimethoxy-19-methyl-, methyl ester, (3-beta,19-alpha,20-alpha)-;Reserpilin | | CAS: | 131-02-2 | | MF: | C23H28N2O5 | | MW: | 412.48 | | EINECS: | 2050053 | | Product Categories: | | | Mol File: | 131-02-2.mol |  |
| | methyl (3beta,19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate Chemical Properties |
| alpha | D20 -38° (ethanol); -14° (c = 1.5 in pyridine); -12° (c = 1.7 in chloroform) | | Boiling point | 180-185 °C(Press: 0.01 Torr) | | density | 1.31±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 17.95±0.60(Predicted) | | form | A solid |
| RIDADR | 1544 | | HazardClass | 6.1(b) | | PackingGroup | III | | Toxicity | guinea pig,LDLo,intravenous,19mg/kg (19mg/kg),Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 600, 1973. |
| | methyl (3beta,19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate Usage And Synthesis |
| Description | An amorphous alkaloid present in Rauwolfia canescens and R. serpentina, the alkaloid forms several crystalline salts and derivatives including the hydrochloride, m.p. 205-7°C; [α]24D - 40° (c 0.44, EtOH); the tartrate, m.p. 190-
2°C; [α]20D - 50° (c 1.0, H20); the oxalate, m.p. 252°C; [α]20D - 4° (c 0.2,
aqueous EtOH); the picrate, m.p. 173°C and the di-p-toluyl-L-tartrate, m.p.
194- 5° C (dec.). | | Definition | ChEBI: Reserpiline is a yohimban alkaloid. | | References | Klohs et al., Chem. & Ind., 1264 (1954)
Stoll, Hoffmann, Brunner., Helv. Chim. Acta, 38,270 (1955)
Shamma, Richey., J. Amer. Chem. Soc., 85,2507 (1963) |
| | methyl (3beta,19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate Preparation Products And Raw materials |
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