16alpha,17,21-trihydroxypregna-1,4,9(11)-triene-3,20-dione 21-acetate

16alpha,17,21-trihydroxypregna-1,4,9(11)-triene-3,20-dione 21-acetate Basic information
Product Name:16alpha,17,21-trihydroxypregna-1,4,9(11)-triene-3,20-dione 21-acetate
Synonyms:16alpha,17,21-trihydroxypregna-1,4,9(11)-triene-3,20-dione 21-acetate;16,17-Dihydroxypregna-1,4,9(11)-triene-3,20-dione 21-acetate;16-alpha,17-alpha-dihydroxy-3,20-dioxopregna- 1,4,9(11)-trien-21-yl acetate;Pregna-1,4,9(11)-triene-16,17-diol-3,20-dione 21-acetate;21-(Acetyloxy)-16α,17-dihydroxypregna-1,4,9(11)-triene-3,20-dione;(16α)-21-Acetyloxy-16,17-dihydroxy-pregna-1,4,9(11)-triene-3,20-dione;BNKY015-BD01;Budesonide Impurity 12
CAS:77017-20-0
MF:C23H28O6
MW:400.46482
EINECS:278-593-2
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
Mol File:77017-20-0.mol
16alpha,17,21-trihydroxypregna-1,4,9(11)-triene-3,20-dione 21-acetate Structure
16alpha,17,21-trihydroxypregna-1,4,9(11)-triene-3,20-dione 21-acetate Chemical Properties
Melting point 213-215 °C(Solv: acetone (67-64-1); ligroine (8032-32-4))
Boiling point 576.7±50.0 °C(Predicted)
density 1.31±0.1 g/cm3(Predicted)
solubility soluble in Acetone, Dichloromethane
pka11.92±0.70(Predicted)
Water Solubility 38.72mg/L at 25℃
LogP2.26 at 25℃
Safety Information
MSDS Information
16alpha,17,21-trihydroxypregna-1,4,9(11)-triene-3,20-dione 21-acetate Usage And Synthesis
UsesIntermediate in the preparation of antiinflammatory compounds.
16alpha,17,21-trihydroxypregna-1,4,9(11)-triene-3,20-dione 21-acetate Preparation Products And Raw materials
Raw materials3,20-Dioxopregna-1,4,9(11),16-tetraen-21-yl acetate
Preparation ProductsPrednisone Impurity 13
16α,17-[(1RS)-Butylidenebis(oxy)]-11β-hydroxy-17-(hydroxyMethyl)-D-hoMoandrosta-1,4-diene-3,17a-dione (Mixture of DiastereoMers) 21-Dehydro Budesonide IMp. A (EP): 11β,16α,17,21-Tetrahydroxy-pregna-1,4-diene-3,20-dione (16-Hydroxy- prednisolone) Budesonide Impurity H Budesonide iMpurity E Budesonide Impurity 7 IMp. B (EP): 16α,17-[(1RS)-Ethylidenebis(oxy)]-11β,21-dihydroxypregna-1,4-diene-3,20-dione 21-Acetoxy-11-oxo-16α,17α-propylMethylenedioxpregna-1,4-diene-3,20-dione (11β,16α)-21-(Acetyloxy)-11,16,17-trihydroxypregna-1,4,14-triene-3,20-dione Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9,11-epoxy-16,17-dihydroxy-, (9β,11β,16α)- Budesonide Impurity 30 Budesonide Impurity 21 Prednisone 17, 21-Diacetate Budesonide Impurity 28 11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione Budesonide iMpurity F Budesonide Impurity 11 Budesonide Impurity 5

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