thonzylamine

thonzylamine Basic information
Product Name:thonzylamine
Synonyms:thonzylamine;N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyrimidin-2-yl)ethane-1,2-diamine;N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyrimidin-2-ylethane-1,2-diamine;N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(2-pyrimidinyl)-1,2-ethanediamine;N-[(4-Methoxyphenyl)methyl]-N',N'-dimethyl-N-(2-pyrimidinyl)-1,2-ethanediamine;N-[2-(Dimethylamino)ethyl]-N-(4-methoxybenzyl)pyrimidin-2-amine;NCI-C-60708;Neohetramine
CAS:91-85-0
MF:C16H22N4O
MW:286.37
EINECS:202-103-8
Product Categories:
Mol File:91-85-0.mol
thonzylamine Structure
thonzylamine Chemical Properties
Boiling point 428.74°C (rough estimate)
density 1.0426 (rough estimate)
refractive index 1.5850 (estimate)
storage temp. Hygroscopic, Refrigerator, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form Oil
pkapKa 2.17 (Uncertain);8.96 (Uncertain)
color Light Brown to Brown
Water Solubility 5.441g/L(37.5 ºC)
Stability:Hygroscopic
CAS DataBase Reference91-85-0
EPA Substance Registry SystemThonzylamine (91-85-0)
Safety Information
MSDS Information
thonzylamine Usage And Synthesis
UsesThonzylamine is a selective H1-histamine receptor anatagonists. Tropine esterase inhibitor.
DefinitionChEBI: N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyrimidinyl)ethane-1,2-diamine is a member of methoxybenzenes.
General DescriptionAn oily liquid. Used (in the form of the hydrochloride) as an antihistaminic.
Reactivity Profilethonzylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health HazardACUTE/CHRONIC HAZARDS: Toxic. Hazardous decomposition products.
thonzylamine Preparation Products And Raw materials
HEXADECYL[2-([P-METHOXYBENZYL]-2-PYRIMIDINYLAMINO)ETHYL]DIMETHYL-AMMONIUM BROMIDE thonzylamine N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine thonzylamine hydrochloride Hetramine

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